Retreatment with pembrolizumab in advanced non-small cell lung cancer patients previously treated with nivolumab: emerging reports of 12 cases

…, N Uchida, O Kanai, M Okamura, K Nakatani… - Cancer Chemotherapy …, 2018 - Springer
Purpose After approval of anti-programmed cell death (PD)-1 antibodies, treatment for non-small
cell lung cancer (NSCLC) has drastically changed. However, even in patients with …

Impact of COVID‐19 pandemic on lung cancer treatment scheduling

K Fujita, T Ito, Z Saito, O Kanai, K Nakatani… - Thoracic …, 2020 - Wiley Online Library
The current coronavirus disease 2019 (COVID‐19) pandemic is associated with a heavy
burden on the mental and physical health of patients, regional healthcare resources, and global …

Retreatment with anti-PD-L1 antibody in advanced non-small cell lung cancer previously treated with anti-PD-1 antibodies

…, O Kanai, M Okamura, K Nakatani… - Anticancer …, 2019 - ar.iiarjournals.org
Aim: To evaluate the efficacy and safety of re-treatment with anti-programmed death (PD)-L1
antibody (atezolizumab) after anti-PD-1 antibody (nivolumab/pembrolizumab) treatment in …

Acute progression of aspergillosis in a patient with lung cancer receiving nivolumab

N Uchida, K Fujita, K Nakatani… - Respirology Case …, 2018 - Wiley Online Library
A 65‐year‐old man with chronic progressive pulmonary aspergillosis (CPPA) was admitted
for the treatment of lung adenocarcinoma while receiving an immune checkpoint inhibitor, …

Retreatment with anti‐PD‐1 antibody in non‐small cell lung cancer patients previously treated with anti‐PD‐L1 antibody

…, M Okamura, M Hashimoto, K Nakatani… - Thoracic …, 2020 - Wiley Online Library
Background This study evaluated the efficacy and safety of retreatment with anti‐programmed
death 1 (anti‐PD‐1) antibodies in patients with advanced non‐small cell lung cancer (…

Incidence of active tuberculosis in lung cancer patients receiving immune checkpoint inhibitors

…, M Okamura, M Hashimoto, K Nakatani… - Open Forum …, 2020 - academic.oup.com
Although it ameliorates lung cancer, immunotherapy with immune checkpoint inhibitors (ICIs)
presents complications of infectious diseases, including tuberculosis. Incidence of …

Small cell transformation of non‐small cell lung cancer under immunotherapy: Case series and literature review

…, M Okamura, M Hashimoto, K Nakatani… - Thoracic …, 2021 - Wiley Online Library
In advanced lung cancer treatment, immunotherapy provides durable responses in some
patients. However, other patients experience progressive disease and the resistance …

A Phase II Trial on Osimertinib as a First-Line Treatment for EGFR Mutation-Positive Advanced NSCLC in Elderly Patients: The SPIRAL-0 Study

…, S Tanzawa, K Minato, K Nakatani… - The …, 2022 - academic.oup.com
Background Osimertinib is one of the standard first-line treatments for advanced non-small
cell lung cancer in patients with epidermal growth factor receptor (EGFR) mutations, because …

Serial interferon-gamma release assay in lung cancer patients receiving immune checkpoint inhibitors: a prospective cohort study

…, T Imakita, M Okamura, K Nakatani… - Cancer Immunology …, 2022 - Springer
Recent advancements in cancer immunotherapy using immune checkpoint inhibitors (ICIs)
have received considerable attention. Although advantageous, ICI therapies cause unique …

Development of Mycobacterium avium Complex Lung Disease in Patients With Lung Cancer on Immune Checkpoint Inhibitors

…, O Kanai, M Okamura, K Nakatani… - Open Forum …, 2020 - academic.oup.com
Immunotherapy with immune checkpoint inhibitors (ICIs), while ameliorating lung cancer,
can cause infectious diseases, including tuberculosis, in addition to immune-related …