γ-Aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism

…, M Tsuji, N Segawa, H Masuda, K Takahara… - Cancer research, 2003 - AACR
We investigated expression of γ-aminobutyric acid (GABA), glutamate decarboxylase, and
matrix metalloproteinase (MMP) in the prostates of patients with cancer or benign prostatic …

microRNA-145 mediates the inhibitory effect of adipose tissue-derived stromal cells on prostate cancer

K Takahara, M Ii, T Inamoto, T Nakagawa… - Stem cells and …, 2016 - liebertpub.com
Adipose-derived stromal cell (ASC), known as one of the mesenchymal stem cells (MSCs),
is a promising tool for regenerative medicine; however, the effect of ASCs on tumor growth …

Incidence of urethral stricture after bipolar transurethral resection of the prostate using TUR is: Results from a randomised trial

…, K Minami, R Oide, H Uehara, K Takahara… - BJU …, 2015 - Wiley Online Library
Objectives To assess whether bipolar transurethral resection of the prostate ( B ‐ TURP )
using the TUR is ® system has a similar level of efficacy and safety to that of the traditional …

[HTML][HTML] MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells

…, N Sugito, Y Kuranaga, T Inamoto, K Takahara… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The Warburg effect is a well-known feature in cancer-specific metabolism. We previously
reported on the role of microRNA (miR)-145 as a tumor-suppressor in human bladder cancer (…

Insulin-like growth factor-I induces CLU expression through Twist1 to promote prostate cancer growth

…, M Shiota, E Beraldi, D Thaper, K Takahara… - Molecular and cellular …, 2014 - Elsevier
Clusterin (CLU) is cytoprotective molecular chaperone that is highly expressed in castrate-resistant
prostate cancer (CRPC). CRPC is also characterized by increased insulin-like …

[HTML][HTML] A panel of microRNA signature as a tool for predicting survival of patients with urothelial carcinoma of the bladder

…, H Uehara, Y Akao, N Ibuki, K Komura, K Takahara… - Disease …, 2018 - hindawi.com
Introduction and Objectives. MicroRNA (miRNA) expression is altered in urologic malignancies,
including urothelial carcinoma of the bladder (UCB). Individual miRNAs have been …

Adipose-derived stromal cells inhibit prostate cancer cell proliferation inducing apoptosis

K Takahara, M Ii, T Inamoto, K Komura, N Ibuki… - Biochemical and …, 2014 - Elsevier
Mesenchymal stem cells (MSCs) have generated a great deal of interest in the field of
regenerative medicine. Adipose-derived stromal cells (AdSCs) are known to exhibit extensive …

C-reactive protein-albumin ratio as a prognostic factor in renal cell carcinoma–A data from multi-institutional study in Japan

…, H Hirano, H Nomi, N Ibuki, K Takahara… - … Oncology: Seminars and …, 2019 - Elsevier
Introduction The C-reactive protein to albumin ratio (CAR) has been shown to provide prognostic
information in several cancers. The objective in the study is to examine the prognostic …

[HTML][HTML] A novel combination RNAi toward Warburg effect by replacement with miR-145 and silencing of PTBP1 induces apoptotic cell death in bladder cancer cells

…, M Kumazaki, T Tsujino, K Takahara… - International journal of …, 2017 - mdpi.com
Bladder cancer is one of the most difficult malignancies to control. We explored the use of a
novel RNA-interference method for a driver oncogene regulating cancer specific energy …

Risk factors for postoperative ileus after robot‐assisted radical cystectomy with intracorporeal urinary diversion

…, K Hasegawa, M Kozako, K Takahara… - … Journal of Urology, 2022 - Wiley Online Library
Objectives To evaluate the risk factors for postoperative ileus in patients who underwent
robot‐assisted radical cystectomy with intracorporeal urinary diversion. Methods We …