CD147 and matrix metalloproteinase‐2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma

…, K Nakada, K Yanaga, K Yamada, K Ohkawa… - Cancer, 2004 - Wiley Online Library
BACKGROUND The authors investigated whether the presence of matrix metalloproteinase‐2
(MMP‐2) and its inducer, CD147, in cancerous esophageal lesions and surrounding …

Hypoxia promotes glycogen synthesis and accumulation in human ovarian clear cell carcinoma

…, A Okamoto, T Tanaka, K Ohkawa - International …, 2012 - spandidos-publications.com
Ovarian clear cell carcinoma (OCCC) has several significant characteristics based on
molecular features that are distinct from those of ovarian high-grade serous carcinoma. Cellular …

[PDF][PDF] Mobility and effects on vase life of silver-containing compounds in cut rose flowers

K Ohkawa, Y Kasahara, JN Suh - HortScience, 1999 - journals.ashs.org
The effects of silver-containing compounds used for prolonging the vase life of cut rose (Rosa
hybrida L.‘Asami Red’) flowers were investigated. Silver nitrate and RNA-Ag+ tris (a …

[PDF][PDF] Reversal of heat-induced resetting in Eustoma grandiflorum with low temperatures

K Ohkawa, T Yoshizumi, M Korenaga… - HortScience, 1994 - journals.ashs.org
Ohkawa et al.(1991) reported that E. grandiflorum seeds are sensitive to high temperature,
from water absorption through germination during early growth and until two leaf pairs have …

Serum concentrations of free ubiquitin and multiubiquitin chains

…, H Sawada, H Yokosawa, K Ohkawa - Clinical …, 1997 - academic.oup.com
Ubiquitin, which can conjugate with cellular proteins, is classified into two forms: free ubiquitin
and multiubiquitin chains. The latter is active as a signal for degradation of the targeted …

Functional compartmentation of acetaldehyde oxidation in rat liver

R Parrilla, K Ohkawa, KO Lindros… - Journal of Biological …, 1974 - Elsevier
Perfused rat liver and suspensions of isolated rat liver cells have been used to study the
influence of the transaminase inhibitors aminooxyacetate and dl-cycloserine on the rate of …

[PDF][PDF] CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver

…, K Chiba, T Masaki, H Aizaki, K Ohkawa… - …, 2003 - Wiley Online Library
CYP3A is responsible for approximately 50% of the therapeutic drug‐metabolizing activity
in the liver. The present study was undertaken to establish the CYP3A4 inducible model for …

Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma

K Ohkawa, T Hatano, K Yamada, K Joh, K Takada… - Cancer research, 1993 - AACR
A bovine serum albumin-conjugated doxorubicin via the glutaraldehyde bridge (BSA-DXR
conjugate) showed potent dose-dependent inhibition of cell growth against daunorubicin-…

Transplantation of liver organoids in the omentum and kidney

…, M Saito, H Maehashi, H Nomoto, K Ohkawa… - Artificial …, 2011 - Wiley Online Library
Liver organoids were reconstructed by mouse‐immortalized hepatocytes and nonparenchymal
cells (sinusoidal endothelial cells and hepatic stellate cells) in a radial‐flow bioreactor (…

Profiling gene expression ratios of paired cancerous and normal tissue predicts relapse of esophageal squamous cell carcinoma

…, Y Suzuki, T Yamamoto, K Yanaga, K Ohkawa… - Cancer research, 2003 - AACR
Esophageal squamous cell carcinoma has heterogeneous clinical outcomes that cannot be
predicted well using any existing clinical or molecular prognostic factors. Gene expression …