The involvement of HLA-E and-F in pregnancy

A Ishitani, N Sageshima, K Hatake - Journal of reproductive immunology, 2006 - Elsevier
The human MHC class I genes, HLA-E, -F and -G are referred to as non-classical or class Ib
genes and are distinguished from their close relatives (the classical HLA class I genes) by …

Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition

…, N Lee, N Dorofeeva, K Hatake… - The Journal of …, 2003 - journals.aai.org
In this study we focused on the structure and expression of the HLA-E, F, and G class I
complexes in placental tissue. Structural analysis included an examination of the peptides bound …

The surface expression of HLA-F on decidual trophoblasts increases from mid to term gestation

…, M Nakanishi, Y Hayashi, K Hatake… - Journal of reproductive …, 2006 - Elsevier
HLA-F has recently only begun to be studied in earnest, and has been thought not to be
expressed on the cell surface. However, in our previous report, we demonstrated surface …

Effect of aging on endothelium-dependent vascular relaxation of isolated human basilar artery to thrombin and bradykinin.

K Hatake, E Kakishita, I Wakabayashi, N Sakiyama… - Stroke, 1990 - Am Heart Assoc
Using strips of human basilar arteries mounted in organ chambers to record isometric
tension, we investigated vascular reactivity to thrombin and bradykinin. Both agents produced …

Association between soluble MICA levels and disease stage IV oral squamous cell carcinoma in Japanese patients

…, Y Yamanaka, K Yamamoto, A Ishitani, K Hatake… - Human immunology, 2008 - Elsevier
The soluble form of major histocompatibility complex class I–related chain A (MICA) is released
from the surface of tumor cells of epithelial origin. Although MICA expressed on the cell …

Effect of alcohol on vascular function

R Kudo, K Yuui, S Kasuda, K Hatake - Nihon Arukoru Yakubutsu …, 2015 - europepmc.org
Vascular function is regulated by a balance of vasoconstriction and vasorelaxation. Disorder
in this balance due to alcohol consumption causes various clinical conditions. In this review…

Impairment of endothelium-dependent relaxation in human basilar artery after subarachnoid hemorrhage.

K Hatake, I Wakabayashi, E Kakishita, S Hishida - Stroke, 1992 - Am Heart Assoc
The goal of this study was to determine the alterations in vascular reactivity of human basilar
artery after subarachnoid hemorrhage. Human basilar arteries were obtained from subjects …

Soluble MICB serum levels correlate with disease stage and survival rate in patients with oral squamous cell carcinoma

…, Y Imai, Y Nakagawa, K Hatake… - Anticancer …, 2010 - ar.iiarjournals.org
Background: Expression of ligands of natural killer group 2D (NKG2D) immunoreceptors,
such as major histocompatibility complex class I-related chain A/B (MICA/B), has been …

Diminution of contractile response of the aorta from endotoxin-injected rats

I Wakabayashi, K Hatake, E Kakishita… - European journal of …, 1987 - Elsevier
The contractility of a helical strip of the thoracic aorta was studied in rats injected
intraperitoneally with endotoxin. The contractile response to any of the agonistic agents, KCl, …

Soluble HLA-G is absent from human embryo cultures: a reassessment of sHLA-G detection methods

…, N Takeda, Y Odawara, M Nakanishi, K Hatake… - Journal of reproductive …, 2007 - Elsevier
In recent years, the number of patients receiving in vitro fertilization (IVF) has been increasing,
though the rate of successful implantations has remained at 10–20%. A major goal of this …