The pathophysiological significance of tumor infiltrating lymphocytes remains controversial.
To clarify their role, we performed clinicopathological analysis of CD8 + T cells in 131 cases …

OBJECTIVE. To identify the determinants of tumor progression, we examined the ablation
zones and patterns of local progression of small single primary hepatocellular carcinomas …

General rules for recording endoscopic findings of esophageal varices were initially proposed
in 1980 and revised in 1991. These rules have widely been used in Japan and other …

A dose-escalation study of cisplatin (CDDP) combined with S-1, a new oral dihydropyrimidine
dehydrogenase inhibitory fluoropyrimidine, was performed to determine the maximum-…

PURPOSE: This study was designed to define the indications of endoscopic polypectomy for
rectal carcinoid tumors and evaluate the diagnostic value of endoscopic ultrasonography. …

Objective Studies in Western populations have shown the association of nonsteroidal anti-inflammatory
drugs (NSAIDs) and upper gastrointestinal bleeding (UGIB). The role of …

Results: The carcinoid tumors measured 10 mm or less in four of the five patients. Two patients
had type A gastritis, and all had hypergastrinemia. There was no evidence of recurrence …

Background: Endoscopic mucosal resection is an established treatment option for early stage
gastric cancer. However, several problems with endoscopic mucosal resection remain to …

Results: The overall prevalence of lymph node metastasis in gastric cancer with submucosal
invasion was 16.5%(62/376). The prevalence of lymph node metastasis was 36.5%(23/63) …

… The amino acid substitution affected the K m values strongly for coumarin and moderately
for FT in the present study. Thus, the amino acid substitution was assumed to change a protein …