Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy

J Drevs, J Fakler, S Eisele, M Medinger… - Anticancer …, 2004 - ar.iiarjournals.org
From previous preclinical findings continuous low dose (metronomic) chemotherapy is thought
to inhibit tumor angiogenesis. This suggests that activated endothelial cells may be more …

[PDF][PDF] An ER assembly line of AMPA-receptors controls excitatory neurotransmission and its plasticity

…, R Sprengel, A Kulik, J Roeper, U Schulte, B Fakler - Neuron, 2019 - cell.com
Excitatory neurotransmission and its activity-dependent plasticity are largely determined by
AMPA-receptors (AMPARs), ion channel complexes whose cell physiology is encoded by …

Mutant α-synuclein enhances firing frequencies in dopamine substantia nigra neurons by oxidative impairment of A-type potassium channels

…, J Schwenk, G Auburger, A Kulik, B Fakler… - Journal of …, 2014 - Soc Neuroscience
Parkinson disease (PD) is an α-synucleinopathy resulting in the preferential loss of highly
vulnerable dopamine (DA) substantia nigra (SN) neurons. Mutations (eg, A53T) in the α-…

[HTML][HTML] OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage

…, M Lesina, C Grimm, B Fakler… - The Journal of …, 2024 - Am Soc Clin Investig
Regulated exocytosis is initiated by increased Ca 2+ concentrations in close spatial proximity
to secretory granules, which is effectively prevented when the cell is at rest. Here we …

Risk factors for early infection following hemiarthroplasty in elderly patients with a femoral neck fracture

…, UJA Spiegl, A Roth, C Josten, JKM Fakler - European Journal of …, 2019 - Springer
Purpose Periprosthetic joint infections (PJI) after hemiarthroplasty for geriatric femoral neck
fractures are a devastating complication that results in serious morbidity and increased …

The effect of a variety of nutrition label format alignments on recognition, application and total comprehension scores of consumers

CJ Geiger, L Fakler-Pauley, RN Mayer - Journal of the American Dietetic …, 1995 - Elsevier
In order for a nutrition label to be effective, consumers must comprehend the format and find
it visually appealing. FDA was frustrated in its attempt to find a format that consumers …

Grundlagen zellulärer Erregbarkeit

B Fakler, C Fahlke - Physiologie des Menschen: mit Pathophysiologie, 2005 - Springer
… Ionen können aus energetischen Gründen die Zellmembran nicht durchqueren.
Wassermoleküle sind elektrische Dipole und können sich in der Nähe von Ladungen so anordnen, …

Hemiarthroplastik bei Oberschenkelhalsbruch im hohen Alter: Auswirkung der präoperativen Wartezeit und des Operationszeitpunkts auf das Risiko periprothetischer …

D Zajonz, J Behrens, AG Brand, A Höch, JKM Fakler… - Der Orthopäde, 2019 - Springer
Background Hemiarthroplasty is an established treatment for femoral neck fractures (FNF)
in old age; however, approximately 20–30% of patients die within 1 year after surgery. …

Prevalence of intellectual disability as a comorbidity of autism spectrum disorder in patients with multidisciplinary examination at the specialized learning center (NEA) …

…, KPP Chaves, VF Horta, DAG Fakler… - Arquivos de Neuro …, 2022 - thieme-connect.com
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized
by clinically significant and persistent deficits in communication and social interactions …

Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany

AG Ziegler, K Kick, E Bonifacio, F Haupt, M Hippich… - Jama, 2020 - jamanetwork.com
Importance Public health screening for type 1 diabetes in its presymptomatic stages may
reduce disease severity and burden on a population level. Objective To determine the …