[HTML][HTML] Platelet activation: the mechanisms and potential biomarkers

SH Yun, EH Sim, RY Goh, JI Park, JY Han - BioMed research …, 2016 - hindawi.com
Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets
play an integral role in intercellular communication, mediating inflammatory and …

Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions

JI Park, SY Tsai, MJ Tsai - The Keio journal of medicine, 2003 - jstage.jst.go.jp
Chicken ovalbumin upstream promoter-transcription factors (COUP-TFs) are one of the most
characterized orphan receptors of the steroid/thyroid hormone receptor superfamily. COUP-…

[HTML][HTML] Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers

JI Park, HR Bae, CG Kim, VA Stonik, JY Kwak - Frontiers in chemistry, 2014 - frontiersin.org
Many marine triterpene glycosides have in vitro and in vivo activities with very low toxicity,
suggesting that they are suitable agents for the prevention and treatment of different diseases, …

COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis

K Tang, X Xie, JI Park, M Jamrich, S Tsai… - …, 2010 - journals.biologists.com
Transcriptional networks, which are initiated by secreted proteins, cooperate with each other
to orchestrate eye development. The establishment of dorsal/ventral polarity, especially …

p53 regulates mitochondrial dynamics by inhibiting Drp1 translocation into mitochondria during cellular senescence

…, JH Yoon, DY Lee, YJ Lee, DH Kim, JI Park… - The FASEB …, 2020 - Wiley Online Library
Cellular senescence acts as an important barrier to tumorigenesis by eliminating precancerous
cells. Previous studies have shown an essential role of the tumor suppressor p53 in …

Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-α

JO Jin, HY Park, Q Xu, JI Park… - Blood, The Journal …, 2009 - ashpublications.org
Dendritic cells (DCs) are the most potent antigen-presenting cells for naive T cells. In this
study, scavenger receptor class A type I and type II (SR-A) were shown to be expressed by …

Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells

…, MK Kim, KS Park, YH Bae, J Yun, JI Park… - Biochemical and …, 2005 - Elsevier
In the present study, we found that serum amyloid A (SAA) stimulated matrix-metalloproteinase-9
(MMP-9) upregulation at the transcription and translational levels in THP-1 cells. SAA …

Differential effects of triterpene glycosides, frondoside A and cucumarioside A2‐2 isolated from sea cucumbers on caspase activation and apoptosis of human …

JO Jin, VV Shastina, SW Shin, Q Xu, JI Park… - FEBS …, 2009 - Wiley Online Library
Frondoside A is a pentaoside having an acetyl moiety at the aglycon ring and xylose as a third
monosaccharide residue. Cucumarioside A 2 ‐2 is a pentaoside having glucose as a third …

15d-PGJ2 Induces Apoptosis by Reactive Oxygen Species–mediated Inactivation of Akt in Leukemia and Colorectal Cancer Cells and Shows In vivo Antitumor …

…, H Han, JY Han, JS Jeong, JY Kwak, JI Park - Clinical Cancer …, 2009 - AACR
Purpose: Recent studies have shown that 15-deoxy-Δ 12, 14 -prostaglandin J 2 (15d-PGJ 2
), a natural ligand for peroxisome proliferator–activated receptor-γ (PPARγ), inhibits cell …

Hydroxyurea induces a senescence-like change of K562 human erythroleukemia cell

JI Park, JS Jeong, JY Han, DI Kim, YH Gao… - Journal of cancer …, 2000 - Springer
Hydroxyurea, a differentiation-inducing agent of human erythroleukemia K562 cells, is commonly
used to treat some types of leukemia. However, the mechanism for its therapeutic effect …