Endometrial cancer is the most common gynecologic cancer in developed countries.
Approximately 3%–14% of endometrial cancers are diagnosed in young women under 40 who …

Background Olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, has previously shown
efficacy in a phase 2 study when given in capsule formulation to all-comer patients with …

Background Data are limited regarding the use of poly(adenosine diphosphate [ADP]–ribose)
polymerase inhibitors, such as veliparib, in combination with chemotherapy followed by …

Background Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has previously
been shown to extend progression-free survival versus placebo when given to patients with …

Purpose The objective of this study was to compare the efficacy and safety of trabectedin
plus pegylated liposomal doxorubicin (PLD) with that of PLD alone in women with recurrent …

OBJECTIVE.: Uterine leiomyosarcoma (LMS) is usually diagnosed after surgery for leiomyoma;
thus tumor morcellation frequently occurs. We evaluated the impact of tumor morcellation …

BACKGROUND. The purpose of this study was to identify problems related to long‐term
quality of life (QOL) and sexual function in cervical cancer survivors. METHODS. The authors …

Background Secondary surgical cytoreduction in women with platinum-sensitive, recurrent
epithelial ovarian, primary peritoneal, or fallopian-tube (“ovarian”) cancer is widely practiced …

BACKGROUND & AIMS: Pancreatic bicarbonate (HCO 3 − ) secretion is important for a
healthy pancreas as well as digestive physiology. However, how human pancreatic duct cells …

RESULTS Of 266 randomly assigned patients, 178 were assigned to olaparib and 88 to
chemotherapy. In patients with measurable disease (olaparib, n= 151; chemotherapy, n= 72), …