High-resolution melting (HRM) analysis is a feasible and powerful method for mutation
scanning of sequence variants. Denatured doubled-stranded DNA can be detected in …

The survival motor neuron gene is present in humans in a telomeric copy, SMN1, and several
centromeric copies, SMN2. Homozygous mutation of SMN1 is associated with proximal …

Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by
degeneration of the anterior horn cells of the spinal cord, leading to muscular paralysis with …

Disruption of circadian rhythm may be a risk factor in the development of breast cancer, but
molecular changes in circadian rhythm controlled genes in breast cancer cells are still …

Circadian rhythm plays an important role in the regulation of digestive system. The human
circadian rhythm is controlled by at least nine circadian genes. The aims of this study are to …

Background The pathogenesis of multiple myeloma involves complex genetic and epigenetic
events. This study aimed to investigate the role and clinical relevance of the long non-…

Disruption of circadian rhythm is believed to play a critical role in cancer development. To
gain further insights into the roles of circadian genes in chronic myeloid leukemia (CML), we …

Spectrin is the major molecular consituent of the red cell membrane skeleton. We have
isolated overlapping human erythroid beta-spectrin cDNA clones and determined 6773 base …

The International Agency for Research on Cancer declared that areca nut was carcinogenic
to human. Areca nut is the main component of betel quid (BQ), which is commonly …

The development of endometrial carcinoma (EC) is a multiple‐step process, which includes
inactivation of tumour suppressor genes, activation of oncogenes, and disturbance of cancer…