User profiles for JAN KOVÁŘ

Jan Kovář

Senior Reserarcher, Institute of International Relations Prague
Verified email at iir.cz
Cited by 225

[HTML][HTML] Microtubule-targeting agents and their impact on cancer treatment

…, V Dostál, M Jelínek, L Libusová, J Kovář… - European journal of cell …, 2020 - Elsevier
Microtubule-targeting agents (MTAs) constitute a diverse group of chemical compounds that
bind to microtubules and affect their properties and function. Disruption of microtubules …

Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters

…, R Václavíková, P Daniel, P Souček, J Kovář - Toxicology and applied …, 2016 - Elsevier
Abstract Development of taxane resistance has become clinically very important issue. The
molecular mechanisms underlying the resistance are still unclear. To address this issue, we …

Assessment and clinical relevance of non-fasting and postprandial triglycerides: an expert panel statement

GD Kolovou, DP Mikhailidis, J Kovar… - Current vascular …, 2011 - ingentaconnect.com
An Expert Panel group of scientists and clinicians met to consider several aspects related to
non-fasting and postprandial triglycerides (TGs) and their role as risk factors for …

[HTML][HTML] Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness

…, V Džupa, J Gojda, V Němcova-Fürstová, J Kovář… - Critical care, 2015 - Springer
Background Mitochondrial damage occurs in the acute phase of critical illness, followed by
activation of mitochondrial biogenesis in survivors. It has been hypothesized that …

[HTML][HTML] Molecular mechanisms of apoptosis induction and its regulation by fatty acids in pancreatic β-cells

J Šrámek, V Němcová-Fürstová, J Kovář - International Journal of …, 2021 - mdpi.com
Pancreatic β-cell failure and death contribute significantly to the pathogenesis of type 2
diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell death is …

A security threat or an economic consequence? An analysis of the news framing of the European Union's refugee crisis

J Kovář - International communication gazette, 2020 - journals.sagepub.com
A developing literature on the securitisation of immigration documents the prominence of
security-based framing, but its prevalence has not been systematically established in Central …

Relationships between right ventricular function, body composition, and prognosis in advanced heart failure

…, M Kotrc, BA Borlaug, T Marek, J Kovar… - Journal of the American …, 2013 - jacc.org
Objectives : This study sought to examine the relationships between right ventricular (RV)
function, body composition, and prognosis in patients with advanced heart failure (HF). …

Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis

…, GD Kolovou, DP Mikhailidis, J Kovar… - Current vascular …, 2011 - ingentaconnect.com
Background/Aim: Triglycerides (TGs) are measured in studies evaluating changes in non-fasting
lipid profiles after a fat tolerance test (FTT); however, the optimal timing for TG …

[HTML][HTML] The role of individual caspases in cell death induction by taxanes in breast cancer cells

…, J Stančíková, I Zanardi, I Ojima, J Kovář - Cancer cell …, 2015 - Springer
Background In previous study we showed that caspase-2 plays the role of an apical caspase
in cell death induction by taxanes in breast cancer cells. This study deals with the role of …

Lymphocyte proliferation is controlled by both iron availability and regulation of iron uptake pathways

PA Seligman, J Kovar, EW Gelfand - Pathobiology, 1992 - karger.com
Cell culture data have demonstrated that transferrin, the major iron (Fe) transport protein, is a
necessary requirement for cellular proliferation. Evidence suggests that transferrin supports …