Circular RNAs are a recently (re-)discovered abundant RNA species with presumed function
as miRNA sponges, thus part of the competing endogenous RNA network. We analysed the …

From birth onward, the lungs are exposed to the external environment and therefore harbor
a complex immunological milieu to protect this organ from damage and infection. We …

Macrophages play a key role in responding to pathogens and initiate an inflammatory response
to combat microbe multiplication. Deactivation of macrophages facilitates resolution of …

Immune responses are tightly regulated to ensure efficient pathogen clearance while avoiding
tissue damage. Here we report that Setdb2 was the only protein lysine methyltransferase …

Phosphatidylinositol 3-kinase has been described as an essential signaling component
involved in the chemotactic cell influx that is required to eliminate pathogens. At the same time, …

Background: Fat grafting is a powerful tool for soft-tissue reconstruction; however, the
science behind recipient bed preparation has not been thoroughly explored. External volume …

HuR is an RNA-binding protein implicated in immune homeostasis and various cancers,
including colorectal cancer. HuR binding to AU-rich elements within the 3′ untranslated region …

In colorectal cancer (CRC) the vitamin D catabolizing enzyme 1,25‐dihydroxyvitamin D 24‐hydroxylase
(CYP24A1) is overexpressed with a potentially significant, positive impact on the …

Phagocytosis and inflammation within the lungs is crucial for host defense during bacterial
pneumonia. Triggering receptor expressed on myeloid cells (TREM)-2 was proposed to …

The pore-forming toxin Panton–Valentine leukocidin (PVL) is carried by community-acquired
methicillin-resistant Staphylococcus aureus and associated with necrotizing pneumonia …