Nephroprotective effects of hydration with magnesium in patients with cervical cancer receiving cisplatin

Y Yamamoto, K Watanabe, I Tsukiyama… - Anticancer …, 2015 - ar.iiarjournals.org
Aim: The present study aimed to assess the efficacy of 15 mEq magnesium supplied as part
of a prehydration regimen in preventing cisplatin-induced nephrotoxicity in patients …

Management of adverse events in patients with metastatic renal cell carcinoma treated with sunitinib and clinical outcomes

…, Y Yamada, K Matsuura, I Tsukiyama… - Anticancer …, 2013 - ar.iiarjournals.org
Patients with progressive renal cell carcinoma who undergo sunitinib treatment, experience
many adverse events (AEs), including thrombopenia and hypertension. Dose reduction or …

Hydration with 15 mEq magnesium is effective at reducingthe risk for cisplatin-induced nephrotoxicity in patients receiving cisplatin (≥ 50 mg/m2) combination …

Y Yamamoto, K Watanabe, I Tsukiyama… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: We aimed to assess whether the efficacy of pre-hydration with 15 mEq magnesium
prevents cisplatin-induced nephrotoxicity in cisplatin regimens (dosage: 50 mg/m 2 or more) for …

Multivariate analysis of risk factors for cisplatin‐induced nephrotoxicity in gynecological cancer

…, K Watanabe, H Matsushita, I Tsukiyama… - Journal of Obstetrics …, 2017 - Wiley Online Library
Aim Risk factors for cisplatin‐induced nephrotoxicity (CIN) vary by population. This study
aimed to assess risk factors for CIN in patients with gynecological cancer. Methods Patients …

Cost‐effectiveness of aprepitant in Japanese patients treated with cisplatin‐containing highly emetogenic chemotherapy

I Tsukiyama, S Hasegawa, Y Ikeda, M Takeuchi… - Cancer …, 2018 - Wiley Online Library
Chemotherapy‐induced nausea and vomiting ( CINV ) remains a major adverse event in
cancer chemotherapy. Although aprepitant is effective in preventing CINV , an increment in …

[HTML][HTML] A cost-effectiveness analysis of gemcitabine plus cisplatin versus gemcitabine alone for treatment of advanced biliary tract cancer in Japan

I Tsukiyama, M Ejiri, Y Yamamoto, H Nakao… - Journal of …, 2017 - Springer
Objectives This study assessed the cost-effectiveness of combination treatment with gemcitabine
and cisplatin compared to treatment with gemcitabine alone for advanced biliary tract …

Lack of contribution of multidrug resistance-associated protein and organic anion-transporting polypeptide to pharmacokinetics of regorafenib, a novel multi-kinase …

K Hotta, J Ueyama, Y Tatsumi, I Tsukiyama… - Anticancer …, 2015 - ar.iiarjournals.org
We investigated whether hepatic multidrug resistance-associated protein 2 (ABCC2) is
involved in the hepatobiliary excretion of regorafenib, a novel multi-kinase inhibitor, using …

[HTML][HTML] Factors associated with early discontinuation of anamorelin in patients with cancer-associated cachexia

I Tsukiyama, T Iwata, T Takeuchi, RI Kato… - Supportive Care in …, 2023 - Springer
Purpose Cancer-associated cachexia, a multifactorial syndrome involving loss of muscle
mass and anorexia, is an unremitting problem for cancer patients. Anamorelin has become …

Contribution of plasma proteins, albumin and alpha 1-acid glycoprotein, to pharmacokinetics of a multi-targeted receptor tyrosine kinase inhibitor, sunitinib, in …

…, J Ueyama, H Nomura, I Tsukiyama… - Anticancer …, 2014 - ar.iiarjournals.org
The present study investigated the role of the major plasma proteins, albumin and α 1 -acid
glycoprotein (AAG), in the pharmacokinetics of sunitinib using Sprague-Dawley (SD) rats and …

The Incidence of Cisplatin-induced Hypomagnesemia in Cervical Cancer Patients Receiving Cisplatin Alone.

…, K Watanabe, H Matsushita, I Tsukiyama… - … zasshi: Journal of the …, 2017 - europepmc.org
Hypomagnesemia is one side effect in patients receiving cisplatin. However, there are few
reports of cisplatin-induced hypomagnesemia in Japan. We retrospectively investigated the …