User profiles for HYUK MOON

Hyuk-June Moon

Senior Researcher
Verified email at kist.re.kr
Cited by 39

[HTML][HTML] MAPK/ERK signaling pathway in hepatocellular carcinoma

H Moon, SW Ro - Cancers, 2021 - mdpi.com
Simple Summary The mitogen-activated protein kinase/extracellular signal-regulated kinase
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …

Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model

SI Chung, H Moon, HL Ju, KJ Cho, KH Han, JW Eun… - Journal of …, 2016 - Elsevier
Background & Aims Liver fibrosis is an increasing health concern worldwide and a major
risk factor for hepatocellular carcinoma (HCC). Although the involvement of Hedgehog …

Barrier to autointegration factor 1, procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase 3, and splicing factor 3b subunit 4 as early‐stage cancer decision markers and …

…, K Kang, S Kim, DH Min, SN Oh, YJ Lee, H Moon… - …, 2018 - Wiley Online Library
An accurate tool enabling early diagnosis of hepatocellular carcinoma (HCC) is clinically
important, given that early detection of HCC markedly improves survival. We aimed to …

Transforming growth factor-β promotes liver tumorigenesis in mice via up-regulation of snail

H Moon, HL Ju, SI Chung, KJ Cho, JW Eun, SW Nam… - Gastroenterology, 2017 - Elsevier
Background & Aims Transforming growth factor beta (TGF-β) suppresses early stages of
tumorigenesis, but also contributes to migration and metastasis of cancer cells. A large number …

[HTML][HTML] Ilizarov treatment of congenital pseudarthrosis of the tibia: a multi-targeted approach using the Ilizarov technique

IH Choi, TJ Cho, HJ Moon - Clinics in orthopedic surgery, 2011 - ncbi.nlm.nih.gov
Congenital pseudarthrosis of the tibia (CPT) is one of the most challenging problems in pediatric
orthopaedics. The treatment goals are osteosynthesis, stabilization of the ankle mortise …

“4-in-1 osteosynthesis” for atrophic-type congenital pseudarthrosis of the tibia

IH Choi, SJ Lee, HJ Moon, TJ Cho… - Journal of Pediatric …, 2011 - journals.lww.com
Background According to the authors' multi-targeted, fibular status-based algorithmic approach
using the Ilizarov technique, ankle stabilization by end-to-end osteosynthesis of the fibula …

YAP/TAZ suppress drug penetration into hepatocellular carcinoma through stromal activation

K Cho, SW Ro, HW Lee, H Moon, S Han, HR Kim… - …, 2021 - Wiley Online Library
Background and Aims HCC is the most predominant type of liver cancer affecting 800,000
people globally each year. Various small‐molecule compounds targeting diverse oncogenic …

c-Myc-driven Hepatocarcinogenesis

H Moon, H Park, SW Ro - Anticancer Research, 2021 - ar.iiarjournals.org
Background/Aim: Dysregulation of the c-Myc gene is frequently found in human hepatocellular
carcinoma (HCC), often accompanied by genetic and epigenetic alterations in other …

Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability

…, Y Song, JR Kim, K Cho, H Moon… - Proceedings of the …, 2017 - National Acad Sciences
Hippo signaling controls the expression of genes regulating cell proliferation and survival
and organ size. The regulation of core components in the Hippo pathway by phosphorylation …

Changes in spatial self-consciousness elicit grid cell–like representation in the entorhinal cortex

HJ Moon, L Albert, E De Falco, C Tasu… - Proceedings of the …, 2024 - National Acad Sciences
Grid cells in the entorhinal cortex (EC) encode an individual’s location in space, integrating
both environmental and multisensory bodily cues. Notably, body-derived signals are also …