Virus-specific cluster of differentiation 8 (CD8+) cytotoxic T cells (CTL) recognize viral
antigens presented on major histocompatibility complex (MHC) class I chains on infected …

Epigenetic alterations such as DNA methylation, histone acetylation, and chromatin remodeling
can control gene expression by regulating gene transcription. DNA methylation is one of …

Cohesins, which mediate sister chromatin cohesion, and CTCF, which functions at chromatin
boundaries, play key roles in the structural and functional organization of chromosomes. …

The leader RNA of the 5′ untranslated region (UTR) of coronaviral genomes contains two
stem–loop structures denoted SL1 and SL2. Herein, we show that SL1 is functionally and …

The goal of this project was to better define the relationship between the endoribonuclease
activity of murine hepatitis virus (MHV) Nsp15 (mNsp15) and its role in virus infection. …

Herpesvirus persistence requires a dynamic balance between latent and lytic cycle gene
expression, but how this balance is maintained remains enigmatic. We have previously shown …

More than 90% of adults have been infected with at least one human herpesvirus, which
establish long-term latent infection for the life of the host. While anti-viral drugs exist that limit …

The 5′ untranslated region (UTR) of the mouse hepatitis virus (MHV) genome contains cis-acting
sequences necessary for transcription and replication. A consensus secondary …

Epstein-Barr virus (EBV) is a human gamma-1 herpesvirus that establishes a lifelong latency
in over 90% of the world's population. During latency, virus exists predominantly as a …

Background Cordyceps militaris has been used as a traditional medicine in Asian countries
for a long time. Different types of Cordyceps extract were reported to have various …