[HTML][HTML] Predictive value of lymphocyte-to-monocyte ratio in the preoperative setting for progression of patients with breast cancer

…, T Hatano, T Takashima, S Tomita, H Motomura… - BMc cancer, 2018 - Springer
Background The lymphocyte-to-monocyte ratio (LMR) has been used as a parameter reflecting
systemic inflammation in several tumors, and is reportedly associated with prognosis in …

[HTML][HTML] Prediction of survival after neoadjuvant chemotherapy for breast cancer by evaluation of tumor-infiltrating lymphocytes and residual cancer burden

…, T Takashima, N Onoda, S Tomita, H Motomura… - BMC cancer, 2017 - Springer
Background The tumor immune environment not only modulates the effects of immunotherapy,
but also the effects of other anticancer drugs and treatment outcomes. These immune …

Prediction of treatment response to neoadjuvant chemotherapy in breast cancer by subtype using tumor-infiltrating lymphocytes

…, T Takashima, S Tomita, H Motomura… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Recent interest has focused on the significance of tumor-infiltrating lymphocytes
(TILs) on the efficacies and outcomes of the treatment in breast cancer (BC). Based on …

Mesenchymal–epithelial transition and tumor vascular remodeling in eribulin chemotherapy for breast cancer

…, T Takashima, S Tomita, H Motomura… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Eribulin mesylate (eribulin) is currently used for the treatment of locally
advanced or metastatic breast cancer (MBC). It is a cytotoxic agent with unique mechanisms …

Pancreatectomy with major arterial resection after neoadjuvant chemoradiotherapy gemcitabine and S-1 and concurrent radiotherapy for locally advanced …

…, K Kimura, B Nakata, S Yamazoe, H Motomura… - Surgery, 2015 - Elsevier
Background Pancreatic cancer (PC) with arterial invasion is currently a contraindication to
resection and has a miserable prognosis. Methods Seventeen patients with locally advanced …

[HTML][HTML] Predictive value of improvement in the immune tumour microenvironment in patients with breast cancer treated with neoadjuvant chemotherapy

…, T Hatano, T Takashima, S Tomita, H Motomura… - ESMO open, 2018 - Elsevier
Background Tumour-infiltrating lymphocytes (TILs) can be used to monitor the immune tumour
microenvironment (iTME) and predict treatment response and outcome in breast cancer. …

[HTML][HTML] Contemporary critical limb ischemia: Asian multidisciplinary consensus statement on the collaboration between endovascular therapy and wound care

…, B Chua, RK George, Y Yokoi, H Motomura… - Cardiovascular …, 2018 - Springer
The burden of peripheral artery disease (PAD) and diabetes in Asia is projected to increase.
Asia also has the highest incidence and prevalence of end-stage renal disease (ESRD) in …

[HTML][HTML] Circulating tumor cell clusters-associated gene plakoglobin is a significant prognostic predictor in patients with breast cancer

…, T Hatano, T Takashima, S Tomita, H Motomura… - Biomarker …, 2017 - Springer
Background Circulating tumor cells (CTCs) are linked to metastatic relapse and are regarded
as a prognostic marker for human cancer. High expression of plakoglobin, a cell adhesion …

Clinical Significance of the Neutrophil–to–Lymphocyte Ratio in Endocrine Therapy for Stage IV Breast Cancer

…, T Hatano, T Takashima, S Tomita, H Motomura… - in vivo, 2018 - iv.iiarjournals.org
Background: Studies have found that patients with cancer exhibit abnormal leukocyte
fractions, such as elevated neutrophil count and diminished lymphocyte count, and that the …

Cd9-positive exosomes derived from cancer-associated fibroblasts might inhibit the proliferation of Malignant melanoma cells

…, T Hatano, H Fujikawa, H Motomura - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Exosomes secreted by various cells in the tumour microenvironment have
been reported to be mediators of intercellular communication that play an important role in …