Study Design. Prospective study. Objective. To examine the efficacy of teriparatide or
bisphosphonate treatment to reduce pedicle screw (PS) loosening after instrumented lumbar …

Background The exact mechanism of knee osteoarthritis (OA)-associated pain is unclear,
whereas mixed evidence of inflammatory pain and neuropathic pain has been noted. We …

Study Design. Prospective trial. Objective. To examine the clinical efficacy of teriparatide for
bone union after instrumented lumbar posterolateral fusion using local bone grafting in …

Purpose Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory).
Animal models of knee OA have shown that sensory nerve fibers innervating the knee are …

Purpose Surgery for lumbar spinal degeneration disease is widely performed. While posterior
decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also …

… Seiji Ohtori, corresponding author * Chikato Mannoji, * Sumihisa Orita, * Kazuyo
Yamauchi, Yawara Eguchi, Nobuyasu Ochiai, Shunji Kishida, Kazuki Kuniyoshi, Yasuchika …

Study Design. Prospective randomized trial. Objective. To examine the effect of the tumor
necrosis factor alpha (TNF-α) inhibitor, etanercept, on radicular pain by its epidural …

Introduction Interleukin-6 (IL-6) is thought to play a crucial role in the radicular pain caused
by lumbar spinal stenosis. However, efficacy of inhibition of IL-6 for sciatica in patients with …

Purpose Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers
innervating the knee have been shown to be significantly damaged in rat models of knee …

Study Design. Immunohistological analysis in an injured intervertebral disk (IVD) model.
Objective. To elucidate and compare in rats the behavior of the sensory nervous system and …