Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4

…, A Shahinian, KP Lee, CB Thompson, H Griesser… - Science, 1995 - science.org
The role of the cell-surface molecule CTLA-4 in the regulation of T cell activation has been
controversial. Here, lymph nodes and spleens of CTLA-4-deficient mice accumulated T cell …

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β

…, R Schmits, JJL Simard, PS Ohashi, H Griesser… - Science, 1995 - science.org
In mice lacking the interleukin-2 receptor β chain (IL-2Rβ), T cells were shown to be
spontaneously activated, resulting in exhaustive differentiation of B cells into plasma cells and the …

Screening for cervical cancer precursors with p16/Ki-67 dual-stained cytology: results of the PALMS study

…, C Bergeron, D Schmidt, H Griesser… - Journal of the …, 2013 - academic.oup.com
Background Pap cytology is known to be more specific but less sensitive than testing for
human papillomavirus (HPV) for the detection of high-grade cervical intraepithelial neoplasia (…

[HTML][HTML] Impaired negative selection of T cells in Hodgkin's disease antigen CD30–deficient mice

…, E Timms, A Wakeham, HW Mittruecker, H Griesser… - Cell, 1996 - cell.com
CD30 is found on Reed–Sternberg cells of Hodgkin's disease and on a variety of non-Hodgkin's
lymphoma cells and is up-regulated on cells after Epstein–Barr virus, human T cell …

Subclassification of diffuse large B-cell lymphomas according to the Kiel classification: distinction of centroblastic and immunoblastic lymphomas is a significant …

…, U Aydemir, S Bierwolf, H Griesser… - Blood, The Journal …, 1997 - ashpublications.org
Among high-grade malignant non-Hodgkin's lymphomas the updated Kiel classification
identifies three major B-cell entities: centroblastic (CB), B-immunoblastic (B-IB), and B-large cell …

Treatment of angioimmunoblastic lymphadenopathy (AILD)-type T-cell lymphoma using prednisone with or without the COPBLAM/IMVP-16 regimen: a multicenter …

W Siegert, A Agthe, H Griesser… - Annals of internal …, 1992 - acpjournals.org
▪ Objective: To describe the clinical course of patients with angioimmunoblastic lymphadenopathy
(AILD)-type lymphoma with a sequential treatment with prednisone and COPBLAM/…

Low dose estriol pessaries for the treatment of vaginal atrophy: a double-blind placebo-controlled trial investigating the efficacy of pessaries containing 0.2 mg and …

H Griesser, S Skonietzki, T Fischer, K Fielder… - Maturitas, 2012 - Elsevier
OBJECTIVE: The aim of the study was to confirm the superior efficacy of estriol containing
pessaries compared to placebo in the treatment of vaginal atrophy. STUDY DESIGN: In a …

Correlation of immunochemical detection of HPV L1 capsid protein in pap smears with regression of high-risk HPV positive mild/moderate dysplasia.

H Griesser, H Sander, R Hilfrich, B Moser… - Analytical and …, 2004 - europepmc.org
Objective To immunostain Pap smears of high-risk (hr) HPV DNA-positive early squamous
lesions for detecting HPV L1 protein. Study design Routinely stained archival slides from 84 …

Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells

…, WP Fung‐Leung, H Griesser… - European journal of …, 1995 - Wiley Online Library
MRL/lpr mice develop a systemic autoimmune disease similar to systemic lupus erythematosus
in humans. The mice show progressive lymphadenopathy due to the accumulation of an …

Performance of p16INK4a-cytology, HPV mRNA, and HPV DNA testing to identify high grade cervical dysplasia in women with abnormal screening results

…, J Rahmsdorf, F Schaffrath, H Griesser… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: The prognostic value of dysplastic lesions of the uterine cervix cannot be
adequately determined by Pap cytology alone. Detection of HPV DNA increases the diagnostic …