Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

…, C Kristiansen, L Madsen, L Fugger, H Scott… - Nature medicine, 1998 - nature.com
The action of tissue Transglutaminase1 (TGase) on specific protein-bound glutamine residues
plays a critical role in numerous biological processes2–5. Here we provide evidence for a …

Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

…, FE Johansen, O Fausa, LM Sollid, J Jahnsen, H Scott… - Gastroenterology, 1998 - Elsevier
Background & Aims: Celiac disease appears to be a T cell–mediated enteropathy induced
by gluten in genetically predisposed individuals. Duodenal biopsy specimens from patients …

[HTML][HTML] The impact of cytomegalovirus infection and disease on rejection episodes in renal allograft recipients

…, KP Nordal, A Hartmann, S Sund, H Scott… - American Journal of …, 2002 - Elsevier
Cytomegalovirus (CMV) infection and disease are potential risk factors for acute allograft
rejection in renal transplant recipients. The present study specifically addresses this issue. …

[HTML][HTML] The molecular basis for oat intolerance in patients with celiac disease

…, B Fleckenstein, Ø Molberg, H Scott… - PLoS …, 2004 - journals.plos.org
Background Celiac disease is a small intestinal inflammatory disorder characterized by
malabsorption, nutrient deficiency, and a range of clinical manifestations. It is caused by an …

Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation

…, DR Sorensen, PM De Angelis, H Scott… - The American journal of …, 2008 - Elsevier
Interleukin (IL)-33 is a novel member of the IL-1 family of cytokines that promotes Th2 responses
in lymphocytes as well as the activation of both mast cells and eosinophils via the ST2 …

Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease

…, EM Nilsen, A Bakka, H Carlsen, P Brandtzaeg, H Scott - Gastroenterology, 1997 - Elsevier
BACKGROUND & AIMS: Most macrophages in the normal intestinal mucosa have a mature
phenotype. In inflammatory bowel disease (IBD), a monocyte-like subset (CD14+ L1+) …

Distribution of a new myelomonocytic antigen (L1) in human peripheral blood leukocytes: immunofluorescence and immunoperoxidase staining features in …

…, P Brandtzaeg, MK Fagerhol, H Scott - American journal of …, 1985 - academic.oup.com
The LI antigen is a highly immunogenic protein of about 36,500 daltons that can be purified
from granulocytes with good yield. Immunocytochemistry with a rabbit anti-serum raised …

T cells from the small intestinal Mucosa of a DR4, DQ7/DR4. DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8

KEA Lundin, H Scott, O Fausa, E Thorsby, LM Sollid - Human immunology, 1994 - Elsevier
CD is an immunologic disease of the small intestine which is precipitated by ingestion of
wheat gliadin. Most patients carry the HLA-DQ (α1 ∗ 0501,β1 ∗ 0201) (DQ2) heterodimer. We …

Noninvasive assessment of myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy

VM Almaas, KH Haugaa, EH Strøm, H Scott, HJ Smith… - Heart, 2014 - heart.bmj.com
Objective Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) imaging
is the reference standard for non-invasive assessment of fibrosis. In hypertrophic …

Increased amount of interstitial fibrosis predicts ventricular arrhythmias, and is associated with reduced myocardial septal function in patients with obstructive …

VM Almaas, KH Haugaa, EH Strøm, H Scott… - Europace, 2013 - academic.oup.com
Aims Reduced echocardiographic strain is associated with ventricular arrhythmias in
hypertrophic cardiomyopathy (HCM) patients. The aim of this cross-sectional study was to …