Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
…, C Kristiansen, L Madsen, L Fugger, H Scott… - Nature medicine, 1998 - nature.com
The action of tissue Transglutaminase1 (TGase) on specific protein-bound glutamine residues
plays a critical role in numerous biological processes2–5. Here we provide evidence for a …
plays a critical role in numerous biological processes2–5. Here we provide evidence for a …
Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
Background & Aims: Celiac disease appears to be a T cell–mediated enteropathy induced
by gluten in genetically predisposed individuals. Duodenal biopsy specimens from patients …
by gluten in genetically predisposed individuals. Duodenal biopsy specimens from patients …
[HTML][HTML] The impact of cytomegalovirus infection and disease on rejection episodes in renal allograft recipients
…, KP Nordal, A Hartmann, S Sund, H Scott… - American Journal of …, 2002 - Elsevier
Cytomegalovirus (CMV) infection and disease are potential risk factors for acute allograft
rejection in renal transplant recipients. The present study specifically addresses this issue. …
rejection in renal transplant recipients. The present study specifically addresses this issue. …
[HTML][HTML] The molecular basis for oat intolerance in patients with celiac disease
…, B Fleckenstein, Ø Molberg, H Scott… - PLoS …, 2004 - journals.plos.org
Background Celiac disease is a small intestinal inflammatory disorder characterized by
malabsorption, nutrient deficiency, and a range of clinical manifestations. It is caused by an …
malabsorption, nutrient deficiency, and a range of clinical manifestations. It is caused by an …
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
…, DR Sorensen, PM De Angelis, H Scott… - The American journal of …, 2008 - Elsevier
Interleukin (IL)-33 is a novel member of the IL-1 family of cytokines that promotes Th2 responses
in lymphocytes as well as the activation of both mast cells and eosinophils via the ST2 …
in lymphocytes as well as the activation of both mast cells and eosinophils via the ST2 …
Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease
…, EM Nilsen, A Bakka, H Carlsen, P Brandtzaeg, H Scott - Gastroenterology, 1997 - Elsevier
BACKGROUND & AIMS: Most macrophages in the normal intestinal mucosa have a mature
phenotype. In inflammatory bowel disease (IBD), a monocyte-like subset (CD14+ L1+) …
phenotype. In inflammatory bowel disease (IBD), a monocyte-like subset (CD14+ L1+) …
Distribution of a new myelomonocytic antigen (L1) in human peripheral blood leukocytes: immunofluorescence and immunoperoxidase staining features in …
…, P Brandtzaeg, MK Fagerhol, H Scott - American journal of …, 1985 - academic.oup.com
The LI antigen is a highly immunogenic protein of about 36,500 daltons that can be purified
from granulocytes with good yield. Immunocytochemistry with a rabbit anti-serum raised …
from granulocytes with good yield. Immunocytochemistry with a rabbit anti-serum raised …
T cells from the small intestinal Mucosa of a DR4, DQ7/DR4. DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8
CD is an immunologic disease of the small intestine which is precipitated by ingestion of
wheat gliadin. Most patients carry the HLA-DQ (α1 ∗ 0501,β1 ∗ 0201) (DQ2) heterodimer. We …
wheat gliadin. Most patients carry the HLA-DQ (α1 ∗ 0501,β1 ∗ 0201) (DQ2) heterodimer. We …
Noninvasive assessment of myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy
VM Almaas, KH Haugaa, EH Strøm, H Scott, HJ Smith… - Heart, 2014 - heart.bmj.com
Objective Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) imaging
is the reference standard for non-invasive assessment of fibrosis. In hypertrophic …
is the reference standard for non-invasive assessment of fibrosis. In hypertrophic …
Increased amount of interstitial fibrosis predicts ventricular arrhythmias, and is associated with reduced myocardial septal function in patients with obstructive …
VM Almaas, KH Haugaa, EH Strøm, H Scott… - Europace, 2013 - academic.oup.com
Aims Reduced echocardiographic strain is associated with ventricular arrhythmias in
hypertrophic cardiomyopathy (HCM) patients. The aim of this cross-sectional study was to …
hypertrophic cardiomyopathy (HCM) patients. The aim of this cross-sectional study was to …