User profiles for HASSAN ASHKTORAB

Hassan Ashktorab

Howard University
Verified email at howard.edu
Cited by 8222

PD‐L1 expression is mainly regulated by interferon gamma associated with JAK‐STAT pathway in gastric cancer

…, LF Kua, V Koh, DT Smoot, H Ashktorab… - Cancer …, 2018 - Wiley Online Library
Despite multidisciplinary treatment for patients with advanced gastric cancer, their prognosis
remains poor. Therefore, the development of novel therapeutic strategies is urgently needed…

Global multi-stakeholder endorsement of the MAFLD definition

…, MJ Armstrong, H Ashktorab… - The lancet …, 2022 - thelancet.com
Correspondence 390 www. thelancet. com/gastrohep Vol 7 May 2022 at least two different
mechanisms of action. Views were divided on the failure of immunomodulators, with 252 (56%…

[HTML][HTML] Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study

…, A Goel, M Hafezi, M Nouraie, H Ashktorab - Molecular cancer, 2008 - Springer
We have identified an alternative pathway of tumorigenesis in sporadic colon cancer, involving
microsatellite instability due to mismatched repair methylation, which may be driven by …

Racial disparity in gastrointestinal cancer risk

H Ashktorab, SS Kupfer, H Brim, JM Carethers - Gastroenterology, 2017 - Elsevier
Cancer from the gastrointestinal tract and its associated excretory organs will occur in more
than 300,000 Americans in 2017, with colorectal cancer responsible for >40% of that burden; …

[HTML][HTML] A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression

…, F Hu, Y Chen, S Chang, X Feng, X Fan, H Ashktorab… - Molecular cancer, 2021 - Springer
Background Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical role in
cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a …

[HTML][HTML] Saffron and its major ingredients' effect on colon cancer cells with mismatch repair deficiency and microsatellite instability

…, A Soleimani, F Praz, G Graziani, H Brim, H Ashktorab - Molecules, 2021 - mdpi.com
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. One of
its subtypes is associated with defective mismatch repair (dMMR) genes. Saffron has many …

Fecal bacteria act as novel biomarkers for noninvasive diagnosis of colorectal cancer

…, A Higashimori, J Fang, H Brim, H Ashktorab… - Clinical Cancer …, 2017 - AACR
Purpose: Gut microbiota have been implicated in the development of colorectal cancer. We
evaluated the utility of fecal bacterial marker candidates identified by our metagenome …

Global epidemiology of nonalcoholic fatty liver disease and perspectives on US minority populations

…, SM Nouraie, AO Laiyemo, H Brim, H Ashktorab - Digestive diseases and …, 2016 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a clinical syndrome predicted to be
the next global epidemic affecting millions of people worldwide. The natural course of this …

[HTML][HTML] Synthetic circular RNA functions as a miR-21 sponge to suppress gastric carcinoma cell proliferation

…, Z Wang, Z Wang, G Zhang, H Ashktorab… - … Therapy-Nucleic Acids, 2018 - cell.com
MicroRNA (miR) sponges containing miR binding sequences constitute a potentially
powerful molecular therapeutic strategy. Recently, naturally occurring circular RNAs (circRNAs) …

[HTML][HTML] Distinct high-profile methylated genes in colorectal cancer

…, M Nouraie, R Green, E Lee, DT Smoot, H Ashktorab - PloS one, 2009 - journals.plos.org
Background Mutations and promoters' methylation of a set of candidate cancer genes (CAN
genes) are associated with progression of colorectal cancer (CRC). We hypothesized that …