[HTML][HTML] Old and new systemic immune-inflammation indexes are associated with overall survival of glioblastoma patients treated with radio-chemotherapy

…, C Giampietro, N Montemurro, N Giannini, G Gadducci… - Genes, 2022 - mdpi.com
Background. Systemic immunity and inflammation indexes (SI) derived from blood cells have
gained increasing attention in clinical oncology as potential biomarkers that are associated …

Impact of recurrence pattern in patients undergoing a second surgery for recurrent glioblastoma

…, I Desideri, M Loi, N Giannini, G Gadducci… - Acta Neurologica …, 2022 - Springer
The impact of different patterns of glioblastoma (GBM) recurrence has not yet been fully
established in patients suitable for a second surgery. Through the present observational study …

Impact of temporalis muscle thickness in elderly patients with newly diagnosed glioblastoma treated with radio or radio-chemotherapy

…, L Faggioni, M Cantarella, S Montrone, G Gadducci… - La radiologia …, 2022 - Springer
Background There is an unmet need for new biomarkers able to predict both the outcomes
of up–front therapy and the compliance of elderly patients diagnosed with glioblastoma. For …

Role of magnetic resonance imaging following postoperative radiotherapy in clinical decision-making of patients with high-grade glioma

…, S Montrone, N Montemurro, G Gadducci… - La radiologia …, 2022 - Springer
Objectives The present study aims to investigate the role of the first magnetic resonances (MRI)
following radio-chemotherapy (RT-CT) in patients diagnosed with high-grade glioma. …

[HTML][HTML] New insights on clinical perspectives of FLASH radiotherapy: from low-to very high electron energy

S Ursino, G Gadducci, N Giannini, A Gonnelli… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Radiotherapy (RT) is performed in approximately 75% of patients with cancer, and its
efficacy is often hampered by the low tolerance of the surrounding normal tissues. Recent …

Adjuvant radiotherapy in patients with pancreatic adenocarcinoma. Is it still appealing in clinical trials? A meta-analysis and review of the literature

…, A Gonnelli, S Montrone, G Gadducci… - Anticancer …, 2021 - ar.iiarjournals.org
Aim. Pancreatic adenocarcinoma is a life-threatening disease with a rising frequency and
the fourth leading cause of cancer death. This review aimed to assess the impact of …

[HTML][HTML] Cancer Stem Cells and Glioblastoma: Time for Innovative Biomarkers of Radio-Resistance?

F Pasqualetti, M Miniati, A Gonnelli, G Gadducci… - Biology, 2023 - mdpi.com
Simple Summary Glioblastoma (GB) is characterized by a high level of resistance to
radiotherapy. Recent studies focused attention on the importance of cancer stem cells (CSC) as …

Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy

…, P Orlandi, E Palladino, N Giannini, G Gadducci… - Investigational New …, 2021 - Springer
This study reports the results of a monocentric prospective analysis conducted with the aim
of evaluating the impact of XRCC1 rs25487, XRCC3 rs861539, XRCC3 rs1799794, RAD51 …

[HTML][HTML] Glioblastoma and Internal Carotid Artery Calcium Score: A Possible Novel Prognostic Partnership?

…, M Cantarella, M Caccese, G Gadducci… - Journal of Clinical …, 2024 - mdpi.com
Purpose: Clinical evidence suggests an association between comorbidities and outcome in
patients with glioblastoma (GBM). We hypothesised that the internal carotid artery (ICA) …

[HTML][HTML] A predictive model of polymetastatic disease from a multicenter large retrospectIve database on colorectal lung metastases treated with stereotactic ablative …

…, A Fodor, A Iurato, F Pasqualetti, G Gadducci… - Clinical and …, 2023 - Elsevier
Aim Stereotactic ablative radiotherapy (SABR) showed increasing survival in oligometastatic
patients. Few studies actually depicted oligometastatic disease (OMD) evolution and which …