User profiles for GIEDRE SILKUNIENE
Giedre SilkunienePhD Verified email at odu.edu Cited by 124 |
[HTML][HTML] Identification of proteins involved in cell membrane permeabilization by nanosecond electric pulses (nsEP)
The study was aimed at identifying endogenous proteins which assist or impede the permeabilized
state in the cell membrane disrupted by nsEP (20 or 40 pulses, 300 ns width, 7 kV/cm…
state in the cell membrane disrupted by nsEP (20 or 40 pulses, 300 ns width, 7 kV/cm…
[HTML][HTML] HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer
A Jakstaite, A Maziukiene, G Silkuniene… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate the expression of HuR in pancreatic ductal adenocarcinoma (PDA) and
to assess the effects of HuR silencing on the expression of cyclooxygenase-2 (COX-2) and …
to assess the effects of HuR silencing on the expression of cyclooxygenase-2 (COX-2) and …
The role of ESCRT-III and Annexin V in the repair of cell membrane permeabilization by the nanosecond pulsed electric field
Exposure of living cells to intense nanosecond pulsed electric field (nsPEF) increases
membrane permeability to small solutes, presumably by the formation of nanometer-size …
membrane permeability to small solutes, presumably by the formation of nanometer-size …
[HTML][HTML] Human antigen R mediated post-transcriptional regulation of inhibitors of apoptosis proteins in pancreatic cancer
…, A Jasukaitiene, G Silkuniene… - World journal of …, 2019 - ncbi.nlm.nih.gov
AIM To determine the association of human antigen R (HuR) and inhibitors of apoptosis
proteins (IAP1, IAP2) and prognosis in pancreatic cancer. METHODS Protein and mRNA …
proteins (IAP1, IAP2) and prognosis in pancreatic cancer. METHODS Protein and mRNA …
Upregulation of cugbp2 increases response of pancreatic cancer cells to chemotherapy
A Jakstaite, A Maziukiene, G Silkuniene… - … archives of surgery, 2016 - Springer
Purpose Altered expression and/or function of ribosomal RNA (rRNA)-binding proteins
CUGBP2/CELF2 might influence post-transcriptional regulation of the HO-1- and COX-2-…
CUGBP2/CELF2 might influence post-transcriptional regulation of the HO-1- and COX-2-…
Hyperthermia potentiates cisplatin cytotoxicity and negative effects on mitochondrial functions in OVCAR-3 cells
The aim of this study was to determine the effects of hyperthermia, cisplatin and their
combination on mitochondrial functions such as glutamate dehydrogenase (GDH) activity and …
combination on mitochondrial functions such as glutamate dehydrogenase (GDH) activity and …
Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses
G Silkuniene, UM Mangalanathan… - Biochemical and …, 2023 - Elsevier
This study explored the role of the Na/K-ATPase (NKA) in membrane permeabilization
induced by nanosecond electric pulses. Using CRISPR/Cas9 and shRNA, we silenced the …
induced by nanosecond electric pulses. Using CRISPR/Cas9 and shRNA, we silenced the …
Real-time imaging of individual electropores proves their longevity in cells
With over 50 years of electroporation research, the nature of cell membrane permeabilization
remains elusive. The lifetime of electropores in molecular models is limited to nano- or …
remains elusive. The lifetime of electropores in molecular models is limited to nano- or …
[HTML][HTML] Stimulated upregulation of HO‑1 is associated with inadequate response of gastric and ovarian cancer cell lines to hyperthermia and cisplatin treatment
…, A Jasukaitiene, G Silkuniene… - Oncology …, 2019 - spandidos-publications.com
Heme oxygenase (HO)‑1 is a heat shock protein induced by hyperthermia, responsible for
cellular resistance to temperature. The aim of this in vitro study was to clarify the response of …
cellular resistance to temperature. The aim of this in vitro study was to clarify the response of …
Epigenetic regulation of APAF-1 through DNA methylation in pancreatic cancer
…, A Mazeike, M Kazokaite, G Silkuniene… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Apoptotic peptidase activating factor 1 (APAF-1) is essential regulator of
apoptosis and inactivation by DNA methylation is common event in numerous cancer types. …
apoptosis and inactivation by DNA methylation is common event in numerous cancer types. …