C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of …

RJ Singh, RL Taylor, GS Reddy… - The Journal of Clinical …, 2006 - academic.oup.com
Context: We have recently introduced liquid chromatography-tandem mass spectrometry (LC-MS/MS)
for 25-hydroxyvitamin D 2 (25OHD 2 ) and 25OHD 3 testing. During subsequent …

Calcitroic acid, end product of renal metabolism of 1, 25-dihydroxyvitamin D3 through the C-24 oxidation pathway

GS Reddy, KY Tserng - Biochemistry, 1989 - ACS Publications
Revised Manuscript Received October 3, 1988 abstract: About a decade ago calcitroic acid
was isolated as a major side chain cleaved water-soluble metabolite of 1, 25-…

Nuclear factor of activated T cells (NFAT) as a molecular target for 1α, 25-dihydroxyvitamin D3-mediated effects

A Takeuchi, GS Reddy, T Kobayashi… - The Journal of …, 1998 - journals.aai.org
The molecular basis of the immunomodulatory properties of 1α, 25-dihydroxyvitamin D 3 (1α,
25 (OH) 2 D 3) remains elusive. We demonstrate here that 1α, 25 (OH) 2 D 3-mediated …

[HTML][HTML] C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and …

…, K Inouye, K Ozono, N Kubodera, GS Reddy… - Journal of Biological …, 2004 - ASBMB
Recently, it was revealed that 1α,25-dihydroxyvitamin D 3 (1α,25(OH) 2 D 3 ) and 24R,25-dihydroxyvitamin
D 3 (24,25(OH) 2 D 3 ) were metabolized to their respective epimers of the …

1α, 25-Dihydroxy-3-epi-vitamin D3, a natural metabolite of 1α, 25-dihydroxy vitamin D3: production and biological activity studies in pulmonary alveolar type II cells

…, P Vouros, J Padbury, DS Rao, GS Reddy - Molecular genetics and …, 2002 - Elsevier
Pulmonary alveolar type II cells have been shown to be a possible target for the secosteroid
hormone, 1α,25-dihydroxyvitamin D 3 [1α,25(OH) 2 D 3 ], during perinatal transition. At …

[PDF][PDF] Vitamin D metabolism

RL HoRsT, TA Reinhardt, GS Reddy - Vitamin D, 2005 - researchgate.net
In 1919, when the field of experimental nutrition was still in its infancy, Sir Edward Mellanby
conducted a classic experiment that for the first time associated the supplementation of …

[PDF][PDF] Data Warehousing, Data Mining, OLAP and OLTP Technologies are essential elements to support decision-making process in industries

GS Reddy, R Srinivasu, MPC Rao… - International Journal on …, 2010 - academia.edu
This paper provides an overview of Data warehousing, Data Mining, OLAP, OLTP technologies,
exploring the features, applications and the architecture of Data Warehousing. The data …

1α,25‐Dihydroxyvitamin D3 and a Variety of its Natural Metabolites Transcriptionally Repress Nuclear‐Factor‐κB‐Mediated Interleukin‐8 Gene Expression

H Harant, PJ Andrew, GS Reddy… - European journal of …, 1997 - Wiley Online Library
Regulation of interleukin‐8 (IL‐8) gene transcription occurs mainly through the sequences ‐94
to ‐71 of the 5′‐flanking region of the IL‐8 gene, involving the transcription factors …

Regulation of vitamin D metabolism in normal human pregnancy

GS REDDY, AW NORMAN, W WILLIS… - The Journal of …, 1983 - academic.oup.com
The increasing serum concentrations of various hormones (PTH, PRL, estrogens, and human
placental lactogen) are hypothesized to regulate 1,25-dihydroxyvitamin D [1,25(OH) 2 D]…

Vitamin D metabolism in human colon adenocarcinoma-derived Caco-2 cells: Expression of 25-hydroxyvitamin D3-1α-hydroxylase activity and regulation of sidechain …

HS Cross, M Peterlik, GS Reddy, I Schuster - The Journal of steroid …, 1997 - Elsevier
1α,25-Dihydroxyvitamin D 3 (1α,25(OH) 2 D 3 ) and its synthetic analogues exhibit structure-related
variations in their growth inhibitory actions in human colon adenocarcinoma-derived …