Age–incidence patterns of primary CNS tumors in children, adolescents, and adults in England
RS Arora, RD Alston, TOB Eden, EJ Estlin… - Neuro …, 2009 - academic.oup.com
Around 25% of all tumors in those 0–14 years of age and 9% in those 15–24 years of age
involve the CNS. They are the most common cause of cancer-related deaths in both age …
involve the CNS. They are the most common cause of cancer-related deaths in both age …
Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine
EJ Estlin - Cancer treatment reviews, 2001 - Elsevier
Across the world, therapy with 6-mercaptopurine (6-MP) and methotrexate (MTX) forms the
basis of the continuing therapy of childhood acute lymphoblastic leukaemia (ALL). In this …
basis of the continuing therapy of childhood acute lymphoblastic leukaemia (ALL). In this …
Clinical and cellular pharmacology in relation to solid tumours of childhood
EJ Estlin, GJ Veal - Cancer treatment reviews, 2003 - Elsevier
Our understanding of the clinical and cellular pharmacology of drugs commonly used in the
treatment of childhood cancer have increased greatly over the past two decades. However, …
treatment of childhood cancer have increased greatly over the past two decades. However, …
Phase I study of temozolomide in paediatric patients with advanced cancer
EJ Estlin, L Lashford, S Ablett, L Price, R Gowing… - British journal of …, 1998 - nature.com
A phase I study of temozolomide administered orally once a day, on 5 consecutive days,
between 500 and 1200 mg m (-2) per 28-day cycle was performed. Children were stratified …
between 500 and 1200 mg m (-2) per 28-day cycle was performed. Children were stratified …
Chronic hypoxia promotes hypoxia-inducible factor-1α–dependent resistance to etoposide and vincristine in neuroblastoma cells
D Hussein, EJ Estlin, C Dive, GWJ Makin - Molecular cancer therapeutics, 2006 - AACR
Hypoxia is widespread in solid tumors as a consequence of poorly structured tumor-derived
neovasculature. Direct measurement of low oxygen levels in a range of adult tumor types …
neovasculature. Direct measurement of low oxygen levels in a range of adult tumor types …
Diffuse brainstem gliomas in children: should we or shouldn't we biopsy?
PA Leach, EJ Estlin, DJ Coope, JA Thorne… - British journal of …, 2008 - Taylor & Francis
The decision to biopsy diffuse pontine gliomas in children remains controversial. There have
been many publications over the last 30 years aiming to address this issue. The prognosis …
been many publications over the last 30 years aiming to address this issue. The prognosis …
A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin
…, MA Little, SM Yule, B Morland, EJ Estlin… - British journal of …, 2001 - nature.com
Pre-clinical studies indicate that cisplatin encapsulated in STEALTH® liposomes (SPI-77)
retains anti-tumour activity, but has a much reduced toxicity, compared to native cisplatin. A …
retains anti-tumour activity, but has a much reduced toxicity, compared to native cisplatin. A …
SenseCam as a rehabilitation tool in a child with anterograde amnesia
K Pauly-Takacs, CJA Moulin, EJ Estlin - Memory, 2011 - Taylor & Francis
We present the case of a 13-year-old boy, CJ, with profound episodic memory difficulties
following the diagnosis of a metastatic intracranial germ cell tumour and subsequent treatment …
following the diagnosis of a metastatic intracranial germ cell tumour and subsequent treatment …
Are reported increases in incidence of primary CNS tumours real? An analysis of longitudinal trends in England, 1979–2003
RS Arora, RD Alston, TOB Eden, EJ Estlin… - European journal of …, 2010 - Elsevier
Reported increases in the incidence of CNS tumours in the developed world in the 1970s to
1990s have been a cause for concern and debate. It still remains to be adequately …
1990s have been a cause for concern and debate. It still remains to be adequately …
Cystic fibrosis in Asians.
IM Bowler, EJ Estlin, JM Littlewood - Archives of disease in childhood, 1993 - adc.bmj.com
The clinical course of cystic fibrosis in nine Pakistani Asians was compared with 18 non-Asian
age and sex matched controls. The Asian patients grew Pseudomonas aeruginosa at an …
age and sex matched controls. The Asian patients grew Pseudomonas aeruginosa at an …