Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells
…, L Fontana, YJ Bignon, L Guy, DJ Bernard-Gallon - In vivo, 2010 - iv.iiarjournals.org
Background: The aim of this study was to determine the effects of soy phytoestrogens on the
methylation of promoter genes in prostate tumors. The incidence of prostate cancer in Asia …
methylation of promoter genes in prostate tumors. The incidence of prostate cancer in Asia …
Genistein and daidzein act on a panel of genes implicated in cell cycle and angiogenesis by polymerase chain reaction arrays in human prostate cancer cell lines
…, N Chalabi, S Satih, YJ Bignon, DJ Bernard-Gallon - Cancer …, 2010 - Elsevier
Background: The prostate cancer most frequently affects men. The ethnic origin and family
antecedents of prostate cancer are established as risk factors. The genetic factors associated …
antecedents of prostate cancer are established as risk factors. The genetic factors associated …
BRCA1 promoter methylation in peripheral blood DNA was identified in sporadic breast cancer and controls
…, F Kwiatkowski, YJ Bignon, DJ Bernard-Gallon - Cancer …, 2012 - Elsevier
Objective Epigenetics, particularly DNA methylation, has recently been shown to be important
in breast cancer initiation. We investigated the clinical and prognostic importance of whole …
in breast cancer initiation. We investigated the clinical and prognostic importance of whole …
Epigenetic modifications in prostate cancer
…, JP Boiteux, YJ Bignon, L Guy, DJ Bernard-Gallon - …, 2014 - Future Medicine
Prostate cancer is the most common cancer in men and the second leading cause of cancer
deaths in men in France. Apart from the genetic alterations in prostate cancer, epigenetics …
deaths in men in France. Apart from the genetic alterations in prostate cancer, epigenetics …
Differential effects of n-3 and n-6 polyunsaturated fatty acids on BRCA1 and BRCA2 gene expression in breast cell lines
DJ Bernard-Gallon, C Vissac-Sabatier… - British Journal of …, 2002 - cambridge.org
Current evidence strongly supports a role for the breast tumour suppressor genes, BRCA1
and BRCA2, in both normal development and carcinogenesis. In vitro observations reported …
and BRCA2, in both normal development and carcinogenesis. In vitro observations reported …
Central adiposity as a major risk factor of ovarian cancer
…, S Satih, YJ Bignon, DJ Bernard-Gallon - Anticancer …, 2009 - ar.iiarjournals.org
The identification of risk factors for ovarian cancer is crucial in prevention of the disease. This
pathology is the leading cause of death from gynecological malignancies. The aim of this …
pathology is the leading cause of death from gynecological malignancies. The aim of this …
DNA repair gene ERCC2, XPC, XRCC1, XRCC3 polymorphisms and associations with bladder cancer risk in a French cohort
…, A Chamoux, YJ Bignon, DJ Bernard-Gallon - Anticancer …, 2008 - ar.iiarjournals.org
In polygenic diseases, association studies look for genetic variation such as polymorphisms
in low penetrance genes, ie genes in interaction with environmental factors. DNA repair …
in low penetrance genes, ie genes in interaction with environmental factors. DNA repair …
Genetic polymorphisms in CYP1A1, CYP1B1, COMT, GSTP1 and NAT2 genes and association with bladder cancer risk in a French cohort
…, YJ Bignon, A Chamoux, DJ Bernard-Gallon - Anticancer …, 2009 - ar.iiarjournals.org
Tobacco smoking and environmental exposures are the main known risk factors for bladder
cancer (BC) via exposure to chemical carcinogens. Genetic differences in the metabolism of …
cancer (BC) via exposure to chemical carcinogens. Genetic differences in the metabolism of …
Gene expression profiling of breast cancer cell lines in response to soy isoflavones using a pangenomic microarray approach
…, L Fontana, YJ Bignon, DJ Bernard-Gallon - Omics: a journal of …, 2010 - liebertpub.com
… J.Bernard-Gallon DJ2003Effects of the phytoestrogens genistein and daidzein on
BRCA2 tumor suppressor gene expression in breast cell linesNutr Cancer45247255. Vissac-Sabatier, …
BRCA2 tumor suppressor gene expression in breast cell linesNutr Cancer45247255. Vissac-Sabatier, …
Expression profiling by whole-genome microarray hybridization reveals differential gene expression in breast cancer cell lines after lycopene exposure
…, S Satih, L Delort, YJ Bignon, DJ Bernard-Gallon - … et Biophysica Acta (BBA …, 2007 - Elsevier
The correlation between diet and variation in gene-expression is an important field which
could be considered to approach cancer pathways comprehension. We examined the effects …
could be considered to approach cancer pathways comprehension. We examined the effects …