User profiles for DIRK STRAUSS

Dirk C Strauss

Royal Marsden Hospital
Verified email at rmh.nhs.uk
Cited by 10517

Variability in patterns of recurrence after resection of primary retroperitoneal sarcoma (RPS): a report on 1007 patients from the multi-institutional collaborative RPS …

A Gronchi, DC Strauss, R Miceli, S Bonvalot… - Annals of …, 2016 - journals.lww.com
Background: Retroperitoneal sarcomas (RPS) are rare tumors composed of several well
defined histologic subtypes. The aim of this study was to analyze patterns of recurrence and …

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label …

…, C Le Péchoux, CJ Swallow, D Strauss… - The Lancet …, 2020 - thelancet.com
Background Unlike for extremity sarcomas, the efficacy of radiotherapy for retroperitoneal
sarcoma is not established. The aim of this study was to evaluate the impact of preoperative …

[PDF][PDF] Fc effector function contributes to the activity of human anti-CTLA-4 antibodies

…, AB Aissa, A Georgiou, YNS Wong, M Smith, D Strauss… - Cancer cell, 2018 - cell.com
With the use of a mouse model expressing human Fc-gamma receptors (FcγRs), we
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab mediate …

[PDF][PDF] Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors

…, A Wotherspoon, N Francis, M Smith, D Strauss… - Immunity, 2017 - cell.com
CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as
a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited …

Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised …

…, R Miceli, S Bonvalot, P Ferguson, DC Strauss… - The Lancet …, 2016 - thelancet.com
Background The current American Joint Committee on Cancer/Union for International Cancer
Control (AJCC/UICC) staging system does not have sufficient details to encompass the …

Technical considerations in surgery for retroperitoneal sarcomas: position paper from E-Surge, a master class in sarcoma surgery, and EORTC–STBSG

…, CP Raut, RE Pollock, P Rutkowski, DC Strauss… - Annals of surgical …, 2012 - Springer
Background Surgery is the principal treatment for retroperitoneal sarcoma. These tumors
typically involve or abut multiple organs and therefore require multivisceral resections. Despite …

Transmission of donor melanoma by organ transplantation

DC Strauss, JM Thomas - The lancet oncology, 2010 - thelancet.com
Transplant-related malignancies are a major contributor to morbidity and mortality in the
organ-recipient population, and most often develop de novo in the immunosuppressed recipient …

Management of primary retroperitoneal sarcoma (RPS) in the adult: an updated consensus approach from the Transatlantic Australasian RPS Working Group

CJ Swallow, DC Strauss, S Bonvalot… - Annals of surgical …, 2021 - Springer
Background Retroperitoneal soft tissue sarcomas comprise a heterogeneous group of rare
tumors of mesenchymal origin that include several well-defined histologic subtypes. In 2015, …

Ultra‐rare sarcomas: a consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities

…, M Sbaraglia, IM Schaefer, DC Strauss… - Cancer, 2021 - Wiley Online Library
Background Among sarcomas, which are rare cancers, many types are exceedingly rare;
however, a definition of ultra‐rare cancers has not been established. The problem of ultra‐rare …

Genome sequencing of mucosal melanomas reveals that they are driven by distinct mechanisms from cutaneous melanoma

…, JM Thomas, A Hayes, D Strauss… - The Journal of …, 2013 - Wiley Online Library
Mucosal melanoma displays distinct clinical and epidemiological features compared to
cutaneous melanoma. Here we used whole genome and whole exome sequencing to …