Did you mean: DAIJIRO HIGASHI 1
Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer
T Kinugasa, QUN Huo, D Higashi… - Anticancer …, 2007 - ar.iiarjournals.org
Background: To understand the molecular and morphological alterations in the tight junction
in colorectal cancer (CRC) tissues, the expression of eight tight junction proteins in normal …
in colorectal cancer (CRC) tissues, the expression of eight tight junction proteins in normal …
Vedolizumab in the treatment of ulcerative colitis: an evidence-based review of safety, efficacy, and place of therapy
N Takatsu, T Hisabe, D Higashi, T Ueki, T Matsui - Core evidence, 2020 - Taylor & Francis
Introduction: Selective blockade of the integrins and mucosal adhesion molecules is a
promising therapeutic strategy for ulcerative colitis (UC). Vedolizumab (VDZ), a humanized IgG1 …
promising therapeutic strategy for ulcerative colitis (UC). Vedolizumab (VDZ), a humanized IgG1 …
Changes in the rate of and trends in colectomy for ulcerative colitis during the era of biologics and calcineurin inhibitors based on a Japanese nationwide cohort study
…, H Ohge, R Futatsuki, K Koganei, A Sugita, D Higashi… - Surgery today, 2019 - Springer
Purpose We evaluated the recent incidence of surgery and the changing surgery trends for
ulcerative colitis (UC) in Japan due to the increasing use of anti-tumor necrosis factor (TNF) …
ulcerative colitis (UC) in Japan due to the increasing use of anti-tumor necrosis factor (TNF) …
Surveillance colonoscopy for ulcerative colitis-associated colorectal cancer offers better overall survival in real-world surgically resected cases
…, A Sugita, M Uchino, D Higashi… - Official journal of the …, 2019 - journals.lww.com
OBJECTIVES: To determine the effectiveness of surveillance colonoscopy (SC) and
optimize its use by assessing real-world surgically resected cases of ulcerative colitis (UC)-…
optimize its use by assessing real-world surgically resected cases of ulcerative colitis (UC)-…
Long‐term course of Crohn's disease in Japan: incidence of complications, cumulative rate of initial surgery, and risk factors at diagnosis for initial surgery
…, Y Takaki, F Hirai, K Yao, D Higashi… - Journal of …, 2015 - Wiley Online Library
Background and Aims: Intestinal complications of stenosis or fistula may occur during the
course of Crohn's disease (CD), and surgery is performed in a fair number of patients. The risk …
course of Crohn's disease (CD), and surgery is performed in a fair number of patients. The risk …
Cancer risk in J apanese C rohn's disease patients: Investigation of the standardized incidence ratio
…, A Koga, N Yoshizawa, D Higashi… - Journal of …, 2013 - Wiley Online Library
Background and Aim There have been very few reported investigations on the standardized
incidence ratio ( SIR ) of intestinal cancer and all cancers other than intestinal cancer with C …
incidence ratio ( SIR ) of intestinal cancer and all cancers other than intestinal cancer with C …
The effect of lentinan combination therapy for unresectable advanced gastric cancer
D Higashi, K Seki, Y Ishibashi, Y Egawa… - Anticancer …, 2012 - ar.iiarjournals.org
Background: Developed as a biological response modifier (BRM), lentinan mitigates patients'
symptoms by boosting the immune system. In combination with S-1 (tegafur, gimeracil, …
symptoms by boosting the immune system. In combination with S-1 (tegafur, gimeracil, …
Rate of reoperation decreased significantly after year 2002 in patients with Crohn's disease
…, A Sugita, M Uchino, K Watanabe, D Higashi… - Clinical …, 2020 - Elsevier
Background & Aims Patients with Crohn’s disease (CD) can require multiple intestinal
surgeries. We examined time trends and risk factors for reoperation in patients with CD who …
surgeries. We examined time trends and risk factors for reoperation in patients with CD who …
Diagnosis and clinical course of ulcerative gastroduodenal lesion associated with ulcerative colitis: possible relationship with pouchitis
…, F Hirai, K Ikeda, A Iwashita, D Higashi… - Digestive …, 2010 - Wiley Online Library
Background and Aim: Ulcerative colitis (UC) is not only characterized by pathological
lesions localized to colonic mucosa, but also to various complications involving other organs, …
lesions localized to colonic mucosa, but also to various complications involving other organs, …
Current state of and problems related to cancer of the intestinal tract associated with Crohn's disease in Japan
D Higashi, H Katsuno, H Kimura, K Takahashi… - Anticancer …, 2016 - ar.iiarjournals.org
Background/Aim: Cancer of the intestinal tract (small and large intestine) associated with
Crohn's disease has a low incidence but can be fatal if it develops. Thus, the key question is …
Crohn's disease has a low incidence but can be fatal if it develops. Thus, the key question is …
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