Recent studies have shown that indoleamine 2,3-dioxygenase (IDO) plays a pivotal role in
the modulation of immune response against tumor and virus infection. Here we demonstrate …

Sorafenib (SRF) is a multi-kinase inhibitor that has been shown to have antitumor activity
against several types of cancers, but the effect of SRF on EBV-transformed B cells is unknown. …

It has been known that melanoma cells can suppress the immune system by the Fas ligand.
The present study investigated whether interleukin(IL)-18, which can enhance Fas ligand …

Galectin-3 is involved in tumor cell proliferation, adhesion, angiogenesis and metastasis.
Galectin-3 promotes β-catenin/Wnt signaling, and β-catenin-related oncogenesis has been …

CD70 is expressed in normal activated immune cells as well as in several types of tumors. It
has been established that anti-CD70 mAb induces complement-dependent death of CD70+ …

Recepteur d’origine nantais (RON, MST1R) is a single-span transmembrane receptor tyrosine
kinase (RTK) aberrantly expressed in numerous cancers, including various solid tumors. …

TGF-β is known to play a major role for the reduced NKG2D expression seen in cancer
patients. However, the mechanisms for reduced TGF-β-induced down-regulation of NKG2D are …

Exosomes are extracellularly secreted vesicles ranging from 40 to 100 nm in diameter that
are thought to play important roles in intercellular communication. Exosomes contain …

… Youn Kyung Houh, Kyung Eun Kim and Sunyoung Park performed the experiments, wrote
and revised the manuscript; Dae Young Hur prepared whole blood samples from donors for …

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is a viral protein expressed in all EBV-infected
cells that induces malignant transformation. EBNA1 is reported to contribute to tumor …