[HTML][HTML] Src: a potential target for the treatment of triple-negative breast cancer

D Tryfonopoulos, S Walsh, DM Collins, L Flanagan… - Annals of oncology, 2011 - Elsevier
Background Triple-negative breast cancers lack expression of estrogen and progesterone
receptors and overexpression of human epidermal growth factor receptor 2 (HER2). Unlike …

[HTML][HTML] Advancing Colorectal Cancer Diagnosis with AI-Powered Breathomics: Navigating Challenges and Future Directions

IK Gallos, D Tryfonopoulos, G Shani, A Amditis… - Diagnostics, 2023 - mdpi.com
Early detection of colorectal cancer is crucial for improving outcomes and reducing mortality.
While there is strong evidence of effectiveness, currently adopted screening methods …

Germline deleterious mutations in genes other than BRCA2 are infrequent in male breast cancer

…, D Kalfakakou, D Mauri, D Tryfonopoulos… - Breast Cancer Research …, 2018 - Springer
Purpose Male breast cancer (MBC) is a rare cancer entity, with mutations in BRCA1 and
BRCA2 genes accounting for ~ 10% of patients. Multiple-gene sequencing has already entered …

Estrogen receptor beta increases sensitivity to enzalutamide in androgen receptor-positive triple-negative breast cancer

…, S Theocharis, I Zoi, D Tryfonopoulos… - Journal of cancer …, 2019 - Springer
d The same western blot as c was carried out 48 h post transfection of MDA-MB 453 cells …
in which western blot band intensities of c and d were evaluated in terms of optical density …

One in three highly selected Greek patients with breast cancer carries a loss-of-function variant in a cancer susceptibility gene

…, I Boukovinas, E Razis, D Tryfonopoulos… - Journal of Medical …, 2020 - jmg.bmj.com
Background Gene panel testing has become the norm for assessing breast cancer (BC)
susceptibility, but actual cancer risks conferred by genes included in panels are not established. …

[HTML][HTML] Gemcitabine and docetaxel as first-line treatment for advanced urothelial carcinoma: a phase II study

A Ardavanis, D Tryfonopoulos, A Alexopoulos… - British journal of …, 2005 - nature.com
The purpose of the study was to investigate the toxicity and efficacy of the combination of
gemcitabine and docetaxel in untreated advanced urothelial carcinoma. Patients with …

Abnormal endothelial function in female patients with hypothyroidism and borderline thyroid function

…, TG Papaioannou, DJ Tryfonopoulos… - International journal of …, 2007 - Elsevier
BACKGROUND: It has been suggested that hypothyroidism is associated with an increased
risk for cardiovascular disease. The aim of this study was to assess non-invasively NO-…

[HTML][HTML] Real-world clinical outcome and toxicity data and economic aspects in patients with advanced breast cancer treated with cyclin-dependent kinase 4/6 (CDK4 …

…, S Karageorgopoulou, E Lalla, D Tryfonopoulos… - ESMO open, 2020 - Elsevier
Background We evaluated real-world clinical outcomes and toxicity data and assessed
treatment-related costs in patients with advanced breast cancer who received treatment with …

Non-allergic nature of docetaxel-induced acute hypersensitivity reactions

A Ardavanis, D Tryfonopoulos, I Yiotis… - Anti-cancer …, 2004 - journals.lww.com
Based on observations of a discrepancy between ‘hypersensitivity’reactions to docetaxel (DT)
and the clinical features of allergic reactions, we explored the hypothesis that DT-induced …

[HTML][HTML] Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis

…, S Kennedy, AM Larkin, D Tryfonopoulos… - British journal of …, 2010 - nature.com
… Images (C) and (D) show specimens that were negative for MDR1/P-gp and MRP-1
staining, respectively. Image (E) represents negative control (scale bar=100 μm in all images; …