The antiinflammatory properties of humic substances: a mini review

CEJ Van Rensburg - Phytotherapy Research, 2015 - Wiley Online Library
Humic substances are effective in the suppression of delayed type hypersensitivity, rat paw
oedema, a graft‐versus‐host reaction and contact hypersensitivity in rats. They reduce the C‐…

Synthesis of new 7-chloroquinolinyl thioureas and their biological investigation as potential antimalarial and anticancer agents

A Mahajan, S Yeh, M Nell, CEJ van Rensburg… - Bioorganic & medicinal …, 2007 - Elsevier
New 7-chloroquinolinyl thiourea derivatives derived from the corresponding 4,7-dichloroquinoline
isothiocyanate were synthesized and evaluated for in vitro antimalarial and anticancer …

Tetramethylpiperidine‐substituted phenazines as novel anti‐plasmodial agents

…, N Cornelius, CEJ van Rensburg - Drug development …, 2000 - Wiley Online Library
Two novel derivatives of clofazimine [3‐(p‐chloroanilino)‐10‐(p‐chlorophenyl)‐2,10‐dihydro‐2‐isopropylimino)phenazine]
and the tetramethylpiperidine (TMP)‐substituted phenazines…

Topical application of oxifulvic acid suppresses the cutaneous immune response in mice

CEJ Van Rensburg, SCK Malfeld… - Drug development …, 2001 - Wiley Online Library
The antiinflammatory activity of topically applied coal‐derived fulvic acids (called oxifulvic
acid) at 4.5% and 9% was compared with that of diclofene sodium at 1% and betamethasone …

A cytotoxic bis (carbene) gold (I) complex of ferrocenyl complexes: synthesis and structural characterisation

…, K Wurst, MJ Nell, CEJ van Rensburg… - New Journal of …, 2008 - pubs.rsc.org
… The viability of cells was determined by the MTT method, as described by van Rensburg
et al. Jurkat cells were the most sensitive, while the CoLo cells were the least sensitive to the …

Antineoplastic activity of a series of ferrocene-containing alcohols

…, JC Swarts, E Kreft, CEJ Van Rensburg - Anticancer …, 2007 - ar.iiarjournals.org
Background: Often potentially good chemotherapeutic drugs find limited clinical use due to
the many negative medical and physical side-effects they may exhibit. To combat these …

Cytotoxicity of a series of ferrocene-containing β-diketones

…, CEJ Van Rensburg, E Kreft, JE Van Lier - Anticancer …, 2008 - ar.iiarjournals.org
Background: Oxidised ferrocenium compounds often possess antineoplastic activity. In
contrast, reduced ferrocene derivatives frequently only show activity if cell components can …

An in-vitro evaluation of the cellular uptake and infraphagocytic bioactivity of clarithromycin (A-56268, TE-031), a new macrolide antimicrobial agent

…, G Joone, CEJ van Rensburg - Journal of Antimicrobial …, 1988 - academic.oup.com
Erythromycin base and its 6-0-methyl derivative clarithromycin were actively accumulated
7.3 ± 1.2-fold and 9.2 ± 2-fold respectively by human neutrophils in vitro. The intraphagocytic …

In vitro Investigation of the Antimicrobial Activities of Novel Tetramethylpiperidine- Substituted Phenazines against Mycobacterium tuberculosis

CEJ van Rensburg, GK Jooné, FA Sirgel, NM Matlola… - Chemotherapy, 2000 - karger.com
The intra- and extracellular activities of 5 novel tetramethylpiperidine (TMP)-substituted
phenazines against Mycobacterium tuberculosis H37Rv (ATCC 27294) were determined and …

Antineoplastic activity of polyaspartamide–ferrocene conjugates

…, EW Neuse, CEJ van Rensburg - Applied …, 1998 - Wiley Online Library
The ferrocene/ferricenium redox system plays a significant role in biological oxidation, reduction
and free‐radical reactions. Of particular interest are the findings of earlier investigations …