Nanoparticle-mediated delivery of functional macromolecules is a promising method for
treating a variety of human diseases. Among nanoparticles, cell-derived exosomes have …

Mesenchymal stem cells (MSCs) are one of the most easily accessible stem cells that can
be obtained from various human tissues. They have raised considerable interests for their …

Background During pregnancy, feto-maternal communication can be mediated through
extracellular vesicles, specifically exosomes, 30- to 150-nm particles released from each cell. …

Platelet-derived growth factor (PDGF) is a potent mitogenic and migratory factor that regulates
the tyrosine phosphorylation of a variety of signalling proteins via intracellular production …

Apoptosis, also known as programmed cell death, is the major type of cell death involved in
normal development, regeneration, proliferation and pathologic degeneration in the central …

Oxidative stresses caused by reactive oxygen species (ROS) can induce rapid depolarization
of inner mitochondrial membrane potential and subsequent impairment of oxidative …

We propose a new hydrophoretic method for continuous blood cell separation using a
microfluidic device composed of slanted obstacles and filtration obstacles. The slanted obstacles …

Objective: We investigated the role of NADPH oxidase 4 (Nox4) on lipopolysaccharide (LPS)-induced
proinflammatory responses by human aortic endothelial cells (HAECs). Methods …

Exosomes are cell-secreted nano-sized vesicles which deliver diverse biological molecules
for intercellular communication. Due to their therapeutic potential, exosomes have been …

Oxidative stress is deeply involved in various brain diseases, including neurodegenerative
diseases, stroke, and ischemia/reperfusion injury. Mitochondria are thought to be the target …