User profiles for CHRISTOPHER G. KEVIL
Christopher KevilVice Chancellor for Research and Professor at LSU Health Shreveport Verified email at lsuhsc.edu Cited by 15584 |
Hydrogen sulfide mediates cardioprotection through Nrf2 signaling
…, A Ramachandran, CB Pattillo, CG Kevil… - Circulation …, 2009 - Am Heart Assoc
Rationale: The recent emergence of hydrogen sulfide (H 2 S) as a potent cardioprotective
signaling molecule necessitates the elucidation of its cytoprotective mechanisms. Objective: …
signaling molecule necessitates the elucidation of its cytoprotective mechanisms. Objective: …
[HTML][HTML] Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing
GK Kolluru, SC Bir, CG Kevil - International journal of vascular …, 2012 - hindawi.com
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted with …
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted with …
[HTML][HTML] Nitrate and nitrite in biology, nutrition and therapeutics
…, M Frenneaux, J Friedman, M Kelm, CG Kevil… - Nature chemical …, 2009 - nature.com
Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to
nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is …
nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is …
[HTML][HTML] Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated
by the enzymatic action of xanthine oxidoreductase, nonenzymatic disproportionation, and …
by the enzymatic action of xanthine oxidoreductase, nonenzymatic disproportionation, and …
[HTML][HTML] Hydrogen sulfide chemical biology: pathophysiological roles and detection
Hydrogen sulfide (H 2 S) is the most recent endogenous gasotransmitter that has been reported
to serve many physiological and pathological functions in different tissues. Studies over …
to serve many physiological and pathological functions in different tissues. Studies over …
Measurement of plasma hydrogen sulfide in vivo and in vitro
The gasotransmitter hydrogen sulfide is known to regulate multiple cellular functions during
normal and pathophysiological states. However, a paucity of concise information exists …
normal and pathophysiological states. However, a paucity of concise information exists …
[HTML][HTML] Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
CG Kevil, DK Payne, E Mire, JS Alexander - Journal of Biological Chemistry, 1998 - ASBMB
Vascular permeability factor/vascular endothelial growth factor stimulates endothelial
proliferation, angiogenesis, and increased vascular permeability in vivo . We investigated …
proliferation, angiogenesis, and increased vascular permeability in vivo . We investigated …
[PDF][PDF] Macrophage metabolism of apoptotic cell-derived arginine promotes continual efferocytosis and resolution of injury
Continual efferocytic clearance of apoptotic cells (ACs) by macrophages prevents necrosis
and promotes injury resolution. How continual efferocytosis is promoted is not clear. Here, we …
and promotes injury resolution. How continual efferocytosis is promoted is not clear. Here, we …
Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis
Chronic tissue ischemia due to defective vascular perfusion is a hallmark feature of peripheral
artery disease for which minimal therapeutic options exist. We have reported that sodium …
artery disease for which minimal therapeutic options exist. We have reported that sodium …
H2O2-mediated permeability: role of MAPK and occludin
H 2 O 2 -mediated elevation in endothelial solute permeability is associated with pathological
events such as ischemia-reperfusion and inflammation. To understand how H 2 O 2 …
events such as ischemia-reperfusion and inflammation. To understand how H 2 O 2 …