Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

…, JR Zibert, T Krejsgaard, CM Bonefeld… - Blood, The Journal …, 2011 - ashpublications.org
Cutaneous T-cell lymphomas (CTCLs) are the most frequent primary skin lymphomas.
Nevertheless, diagnosis of early disease has proven difficult because of a clinical and histologic …

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

…, JO Eriksen, T Krejsgaard, CM Bonefeld… - Blood, The Journal …, 2019 - ashpublications.org
It has been proposed that CD4 T-cell responses to Staphylococcus aureus (SA) can
inadvertently enhance neoplastic progression in models of skin cancer and cutaneous T-cell …

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma

…, D Sasseville, MA Wasik, CM Bonefeld… - Blood, The Journal …, 2016 - ashpublications.org
Cutaneous T-cell lymphoma (CTCL) is characterized by proliferation of malignant T cells in
a chronic inflammatory environment. With disease progression, bacteria colonize the …

[HTML][HTML] Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway

…, KW Eriksen, KL Kopp, CM Bonefeld… - Journal of Investigative …, 2011 - Elsevier
IL-17 is a proinflammatory cytokine that is crucial for the host's protection against a range of
extracellular pathogens. However, inappropriately regulated expression of IL-17 is …

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

…, L Iversen, MA Wasik, CM Bonefeld… - Anticancer …, 2014 - ar.iiarjournals.org
Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphoma (CTCL).
MF is characterized by chronic inflammation dominated by cluster of differentiation 4-positive …

[HTML][HTML] Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

…, D Sasseville, MA Wasik, L Iversen, CM Bonefeld… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal
Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant …

Laser capture microdissection followed by next‐generation sequencing identifies disease‐related micro RNA s in psoriatic skin that reflect systemic micro RNA …

…, B Dyring‐Andersen, CM Bonefeld… - Experimental …, 2015 - Wiley Online Library
Psoriasis is a systemic disease with cutaneous manifestations. Micro RNA s (mi RNA s) are
small non‐coding RNA molecules that are differentially expressed in psoriatic skin; however, …

Elucidating the role of interleukin-17F in cutaneous T-cell lymphoma

…, SB Koralov, KL Kopp, CM Bonefeld… - Blood, The Journal …, 2013 - ashpublications.org
Inappropriately regulated expression of interleukin (IL)-17A is associated with the development
of inflammatory diseases and cancer. However, little is known about the role of other IL-…

[HTML][HTML] Vitamin D Up-Regulates the Vitamin D Receptor by Protecting It from Proteasomal Degradation in Human CD4+ T Cells

…, JPH Lauritsen, A Woetmann, N Ødum, CM Bonefeld… - PloS one, 2014 - journals.plos.org
The active form of vitamin D 3 , 1,25(OH) 2 D 3 , has significant immunomodulatory
properties and is an important determinant in the differentiation of CD4 + effector T cells. The …

Rapid allergen‐induced interleukin‐17 and interferon‐γ secretion by skin‐resident memory CD8+ T cells

…, AR Thomsen, C Geisler, CM Bonefeld - Contact …, 2017 - Wiley Online Library
Background Skin‐resident memory T (T RM ) cells are associated with immunological memory
in the skin. Whether immunological memory responses to allergens in the skin are solely …