User profiles for CARLA INES TASCA

Carla Ines Tasca

Universidade Federal de Santa Catarina
Verified email at ufsc.br
Cited by 5681

[HTML][HTML] Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity

…, CEH Rieg, JT Domingues, T Dal-Cim, CI Tasca… - Toxicology, 2014 - Elsevier
Previous studies demonstrate that glyphosate exposure is associated with oxidative damage
and neurotoxicity. Therefore, the mechanism of glyphosate-induced neurotoxic effects …

Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity

…, H Decker, M Alvarez‐Silva, CI Tasca… - Journal of …, 2008 - Wiley Online Library
Thyroid hormone (T 3 ) regulates the growth and differentiation of rat cerebellar astrocytes.
Previously, we have demonstrated that these effects are due, at least in part, to the increased …

Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice

…, A Zomkowski, ALS Rodrigues, CI Tasca - Journal of psychiatric …, 2016 - Elsevier
Atorvastatin is a cholesterol-lowering statin that has been shown to exert several pleiotropic
effects in the nervous system as a neuroprotective and antidepressant-like agent. …

[HTML][HTML] Involvement of PKA, CaMKII, PKC, MAPK/ERK and PI3K in the acute antidepressant-like effect of ferulic acid in the tail suspension test

…, M Maraschin, ALS Rodrigues, CI Tasca - Pharmacology …, 2012 - Elsevier
Ferulic acid (FA, 4-hydroxy-3-methoxycinnamic acid) is a phytochemical compound naturally
present in several plants and foods that is approved as an antioxidant additive and food …

Increased susceptibility to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor

…, RC Dutra, S Pinton, CI Tasca… - Journal of …, 2014 - content.iospress.com
Familial hypercholesterolemia is caused by inherited genetic abnormalities that directly or
indirectly affect the function of the low-density lipoprotein (LDL) receptor. This condition is …

Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects

…, MM Córdova, L Constantino, CI Tasca… - Molecular …, 2015 - Springer
Inosine is an endogenous nucleoside that has anti-inflammatory and antinociceptive properties.
Inosine is a metabolite of adenosine, and some of its actions suggest the involvement of …

Cerebral cortex, hippocampus, striatum and cerebellum show differential susceptibility to quinolinic acid-induced oxidative stress

…, DB Bertoldo, G Mancini, AF De Bem, CI Tasca - Neurological …, 2015 - Springer
Quinolinic acid (QA) is a NMDA receptor agonist implicated in pathological conditions, such
as neurodegenerative diseases and epilepsy. Time-course responses of different brain …

[HTML][HTML] Synthetic organic compounds with potential for bacterial biofilm inhibition, a path for the identification of compounds interfering with quorum sensing

…, PC Leal, RA Yunes, CBNM de Aguiar, CI Tasca… - International journal of …, 2013 - Elsevier
New unconventional approaches to the development of antimicrobial drugs must target
inhibition of infection stages leading to host colonisation or virulence itself, rather than bacterial …

Anti-cancer effects of fucoxanthin on human glioblastoma cell line

…, RB Derner, RC Garcez, CI Tasca… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Glioblastomas (GBMs) are the most malignant primary brain tumor. New
treatment strategies against the disease are urgently needed, as therapies are not completely …

[HTML][HTML] Guanosine Prevents Spatial Memory Impairment and Hippocampal Damage Following Amyloid-β1–42 Administration in Mice

…, NF Marques, LC Constantino, G Mancini, CI Tasca - Metabolites, 2022 - mdpi.com
Alzheimer’s disease (AD) is a progressive neurodegenerative illness responsible for cognitive
impairment and dementia. Accumulation of amyloid-beta (Aβ) peptides in neurons and …