Despite the large number of antidepressants currently available, it is still necessary to
develop new drugs that combine the efficacy of the older antidepressant with improved safety, …

: Milnacipran is a dual-action antidepressant drug with equivalent inhibitory action at
noradrenaline and serotonin neuronal reuptake systems. This dual action has been demonstrated …

The availability of chemotherapeutic drugs administrable by oral route represents a step
forward in the management of cancer patients. Among oral agents, vinorelbine is particularly …

A retrospective population pharmacokinetic (PPK) analysis was performed in 24 pediatric
patients (PEDS)(0.45–16.7 years old) receiving iv busulfan/cyclophosphamide (iv Bu/Cy 4) …

… for 30 seconds, 72C for 1 minute 30 seconds) for 35 cycles, and lastly 72C for 10 minutes; …
conditions were 96C for 1 minute, (96C for 10 seconds, 50C for 5 seconds, and 60C for 4 …

An IV form of busulfan (IV Bu) has recently become available for high dose conditioning
regimen before haematopoietic stem cell transplantation (HSCT). This IV form is expected to …

… C, partial remission of a refractory non–Hodgkin lymphoma treated with MOVIN 60 mg in a …
C, partial remission of a refractory non–Hodgkin lymphoma treated with MOVIN 60 mg in a 68-…

Introduction Oral busulfan clearance is age-dependent and children experience a wide
variability in plasma exposure. BSA- or age-based dosing is used with therapeutic drug …

… C versus incubation at 4 C for 18 h. The surface membrane staining, in order to identify the
leukocyte subsets, using CD3, CD14 and CD66e in combination with CD45 for lymphocytes, …

Background Vinflunine is a novel vinca alkaloid obtained by semi-synthesis using super-acidic
chemistry to selectively introduce two fluorine atoms at the 20′ position of vinorelbine. In …