Towards the introduction of the 'Immunoscore'in the classification of malignant tumours

…, HK Angell, A Berger, C Lagorce… - The Journal of …, 2014 - Wiley Online Library
The American Joint Committee on Cancer/Union Internationale Contre le Cancer ( AJCC /
UICC ) TNM staging system provides the most reliable guidelines for the routine …

[HTML][HTML] Cancer classification using the Immunoscore: a worldwide task force

…, E Wang, J O'Donnell-Tormey, C Lagorce… - Journal of translational …, 2012 - Springer
Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

…, A Berger, C Lagorce, JP Meyers, C Paustian… - The Lancet, 2018 - thelancet.com
… Harrell's C-statistics was used to assess model performance. … Wittekind C … Sautes-Fridman C

[HTML][HTML] Impact of EGFR expression on colorectal cancer patient prognosis and survival

JP Spano, C Lagorce, D Atlan, G Milano, J Domont… - Annals of oncology, 2005 - Elsevier
Background Epidermal growth factor receptor (EGFR) is overexpressed in many types of
cancers, especially colorectal cancer (CRC), and seems to reflect more aggressive histological …

[PDF][PDF] In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer

…, M Tosolini, G Bindea, C Lagorce… - Journal of clinical …, 2009 - academia.edu
… (C, D) Kaplan-Meier curves illustrate the duration of disease-free survival and overall
survival according to the densities of CD45RO … (B, C) Kaplan-Meier curves for the …

[HTML][HTML] Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to …

…, A Berger, C Lagorce, C Paustian… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …

Prognostic and predictive values of the immunoscore in patients with rectal cancer

…, N Haicheur, AM Todosi, A Kirilovsky, C Lagorce… - Clinical Cancer …, 2014 - AACR
… Biopsy samples were incubated for 32 minutes at 37C with mouse monoclonal antibodies
against CD8 (C8/144B; Dako; 1:50 dilution) and 20 minutes at 37C with rabbit monoclonal …

A diagnostic biopsy-adapted immunoscore predicts response to neoadjuvant treatment and selects patients with rectal cancer eligible for a watch-and-wait strategy

…, B Mlecnik, N Haicheur, T Fredriksen, C Lagorce… - Clinical Cancer …, 2020 - AACR
… Delimitation of the tumoral component excluding normal tissue and low-/high-grade
dysplasia-associated lesions was performed by an experienced pathologist (C. Lagorce). The mean …

Cyclooxygenase‐2 is expressed frequently and early in Barrett's oesophagus and associated adenocarcinoma

C Lagorce, F Paraf, D Vidaud, A Couvelard… - …, 2003 - Wiley Online Library
Aims: To establish the prevalence of cyclooxygenase‐2 (COX‐2) expression in a large
series of resected Barrett's adenocarcinoma and associated preneoplastic lesions and to …

[HTML][HTML] Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge

…, T Voron, G Perkins, C Lagorce-Pages… - World Journal of …, 2015 - ncbi.nlm.nih.gov
… vivo analysis of chemosensitivity of several human gastric cancer samples showed that
SRCC and diffuse-type samples were significantly more sensitive to such drugs as mitomycin C, …