BACKGROUND: It has recently been reported that the polyphenol curcumin has pronounced
anti-carcinogenic, anti-inflammatory and pro-apoptotic properties. This study investigated …

Mitochondria are involved in the development of organ failure in critical care diseases.
However, the mechanisms underlying mitochondrial dysfunction are not clear yet. Inducible …

OBJECTIVES: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder,
primarily affecting the articular structures and synovial membranes of multiple joints. Beside …

Background/Aim: The polyphenol curcumin is produced in the rhizome of Curcuma longa
and exhibits potent anti-inflammatory, antioxidant, and chemopreventive activities. Due to the …

Sulfur bath therapy represents the oldest form of treatment for patients with different types of
rheumatic disorders. However, scientific reports about the beneficial effects of this form of …

AIMS: Reactive oxygen species (ROS) are highly diffusable and reactive molecules which
modulate gene transcription, particularly of pro-inflammatory cytokines which play a crucial …

Hydrogen sulfide (H 2 S) emerged as an essential signaling molecule exerting beneficial
effects in various cardiovascular, neurodegenerative, or musculoskeletal diseases with an …

Hydrogen sulfide (H 2 S) is an important mediator of inflammatory processes. However,
controversial findings also exist, and its underlying molecular mechanisms are largely unknown. …

Background In the vascular system, ATP-sensitive K + -channels are a target for H 2 S. Recent
evidence suggests that H 2 S may also modulate Na + - and Ca 2+ -permeable channels …

Background/Aim: Inhibition of arachidonic acid metabolism by curcumin has been suggested
to be a key mechanism for its anti-carcinogenic action. Recently, we reported on the …