The role of Notch and gamma-secretase inhibition in an ovarian cancer model

MM Shah, M Zerlin, BY Li, TJ Herzog… - Anticancer …, 2013 - ar.iiarjournals.org
Background: The Notch pathway is dysregulated in ovarian cancer. We sought to examine
the role of Notch and gamma-secretase (GS) inhibition in ovarian cancer. Materials and …

Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β-Hydrolase Domain 6 (ABHD6)

…, J Yli-Kauhaluoma, W Vanduffel, I Blakey… - Journal of Medicinal …, 2022 - ACS Publications
Multimodal imaging provides rich biological information, which can be exploited to study drug
activity, disease associated phenotypes, and pharmacological responses. Here we show …

[PDF][PDF] Comparison of methods to support in-hospital navigation

Y Li, M Brown, J Pinchin, J Blakey - international navigation …, 2015 - researchgate.net
2. METHOD 2.1. Participants. Twenty-one healthy volunteers aged 20 to 24 years were
divided into three groups with quasi-random sampling to ensure equal group size and gender …

Regional and local contributions to ambient non-methane volatile organic compounds at a polluted rural/coastal site in Pearl River Delta, China

…, T Wang, DR Blake, IJ Simpson, YH Kwok, YS Li - Atmospheric …, 2006 - Elsevier
Identification of major sources of airborne pollutants and their contribution to pollutant loadings
are critical in developing effective pollution control and mitigation strategies. In this study, …

Synthetic Routes for Heteroatom‐Containing Alkylated/Arylated Polycyclic Aromatic Hydrocarbons

…, L Jiang, H Fu, Z Xie, SR Marder, SB Blakey… - Angewandte …, 2021 - Wiley Online Library
Synthetic routes for heteroatom‐containing polycyclic aromatic hydrocarbons (H‐PAHs)
with alkyl and aryl substitution are demonstrated. Three H‐PAHs, including heteroatom‐…

Uterine tumor resembling ovarian sex cord tumor: report of a case with t (X; 6)(p22. 3; q23. 1) and t (4; 18)(q21. 1; q21. 3)

J Wang, GL Blakey, L Zhang, B Bane… - Diagnostic Molecular …, 2003 - journals.lww.com
Uterine tumor resembling ovarian sex cord tumor (UTROSCT) is a rare tumor of reproductive-age
and postmenopausal women. We present the first case of UTROSCT with cytogenetic …

Advanced heart failure in adult congenital heart disease: the role of renal dysfunction in management and outcomes

…, MA Gatzoulis, EL Heng, S Blakey… - European Journal of …, 2023 - academic.oup.com
Aims Previous studies in adult congenital heart disease (CHD) have demonstrated a link
between renal dysfunction and mortality. However, the prognostic significance of renal …

Development of co-selected single nucleotide polymorphisms in the viral promoter precedes the onset of human immunodeficiency virus type 1-associated …

…, A Wojno, S Passic, K Flaig, E Kilareski, B Blakey… - Journal of …, 2011 - Springer
The long terminal repeat (LTR) regulates gene expression of HIV-1 by interacting with multiple
host and viral factors. Cross-sectional studies in the pre-HAART era demonstrated that …

[HTML][HTML] Anti-inflammatory activity of MTL-CEBPA, a small activating RNA drug, in LPS-stimulated monocytes and humanized mice

…, D Doogan, KW Huang, R Habib, D Blakey… - Molecular Therapy, 2019 - cell.com
Excessive or inappropriate inflammatory responses can cause serious and even fatal
diseases. The CCAAT/enhancer-binding protein alpha (CEBPA) gene encodes C/EBPα, a …

Evidence for a common sex determination mechanism for pistil abortion in maize and in its wild relative Tripsacum

D Li, CA Blakey, C Dewald… - Proceedings of the …, 1997 - National Acad Sciences
Cultivated maize (Zea mays) and several other members of the Tribe Andropogoneae produce
unisexual florets. In maize, the formation of two staminate florets in each spikelet on the …