BACKGROUND & AIMS: Patients with chronic hepatitis C virus (HCV) infection display great
variability in disease activity and progression. Although virus-specific adaptive immune …

BACKGROUND & AIMS: Mathematical modeling of hepatitis C virus (HCV) kinetics indicated
that cellular immune responses contribute to interferon (IFN)-induced clearance of HCV. …

Natural killer (NK) cells exhibit a polarized phenotype with increased cytotoxicity and decreased
interferon gamma (IFN‐γ) production in chronic hepatitis C virus (HCV) infection. Here, …

Objective Ribavirin improves treatment response to pegylated-interferon (PEG-IFN) in chronic
hepatitis C but the mechanism remains controversial. We studied correlates of response …

Micro-abstract In a Phase I dose-finding study of metronomic daily oral vinorelbine in advanced
non-small-cell lung cancer, a recommended dose was established for this therapeutic …

Background/Aim: Despite an expected prognostic disadvantage for upper tract versus lower
tract metastatic urothelial carcinomas (UTUC/LTUC), only few studies have been conducted …

Antigen-specific T cells can be induced by direct priming and cross-priming. To investigate
cross-priming as a vaccination approach dendritic cells were transfected with cytopathogenic …

GILT—A randomised phase III study of oral vinorelbine and cisplatin with concomitant
radiotherapy followed by either consolidation therapy with oral vinorelbine and cisplatin or best …

e15536 Background: The outcome of chemotherapy in patients with metastatic urothelial
carcinoma (UC) of the upper tract (UT) is generally assumed to be worse compared to bladder …

1 Summary Cancer is a leading cause of death worldwide. Despite the improvement of
conventional cancer therapies, the mortality rate remains high and current treatment options are …