… Giuseppe Colucci, Vittorio Gebbia, Giancarlo Paoletti, Francesco Giuliani, Michele
Caruso, Nicola Gebbia, Giacomo Cartenı`, Biagio Agostara, Giuseppe Pezzella, Luigi …

Purpose: To evaluate the endocrinological and clinical activity of a new slow-release
formulation of leuprolide acetate in breast cancer patients. Methods: A total of 50 pre- or …

Breast cancer incidence and mortality rates are markedly lower in the south than in the north
of Europe. This has been ascribed to differences in lifestyle and, notably, dietary habits …

Background Uncertainty exists about the optimal schedule of adjuvant treatment of breast
cancer with aromatase inhibitors and, to our knowledge, no trial has directly compared the …

Although estrogen receptors (ERs) are expressed in human hepatocellular carcinoma (HCC),
several clinical trials have failed to demonstrate the efficacy of antiestrogen treatment in …

Purpose: The main goal of our study was to assess estrogen contents of breast tumor tissues,
having different estrogen receptor status, in relation to long-term follow-up of patients. …

Trastuzumab, a monoclonal antibody against the HER2 receptor, is currently approved as a
part of adjuvant therapy for patients with HER2-overexpressing breast tumors. The Short-…

We have investigated the activity and expression of aromatase enzyme in nontumoral,
cirrhotic, and malignant human liver tissues and cells using both chromatographic and reverse …

The relationship between sex steroids and cancer has been studied for more than a century.
Using an original intact cell analysis, we investigated sex steroid metabolism in a panel of …

PURPOSE: A phase III randomized trial was carried out to compare two schedules of the
vinorelbine (VNR)–cisplatin (CDDP) regimen in patients with locally advanced unresectable …