User profiles for APHRODITI NONNI

Aphrodite Nonni

Associate Professor in Pathology, Medical School, National and Kapodistrian University of …
Verified email at med.uoa.gr
Cited by 2686

Histone deacetylases as new therapeutic targets in triple-negative breast cancer: Progress and promises

…, S Valsami, M Kontos, A Nonni… - Cancer Genomics & …, 2017 - cgp.iiarjournals.org
Triple-negative breast cancer (TNBC) lacks expression of estrogen receptor (ER), progesterone
receptor (PR) and HER2 gene. It comprises approximately 15-20% of breast cancers (…

Triple-negative breast cancer: The progress of targeted therapies and future tendencies

…, A Patsouras, P Farmaki, A Nonni… - Anticancer …, 2019 - ar.iiarjournals.org
Triple-negative breast cancer (TNBC) is characterized by a lack of expression of estrogen
receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (…

[HTML][HTML] The Emerging Role of Histone Deacetylase Inhibitors in Cervical Cancer Therapy

…, MV Karamouzis, G Marinos, K Kontzoglou, A Nonni… - Cancers, 2023 - mdpi.com
Simple Summary Histone deacetylase inhibitors (HDACIs) are a relatively new drug class
with important effects on the epigenetic regulation in cancer, inducing cancer cell death, …

Tumor suppressor PTEN in breast cancer: heterozygosity, mutations and protein expression

…, E Papadimitriou, P Grigoropoulos, A Nonni… - Anticancer …, 2014 - ar.iiarjournals.org
Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is one of the most
frequently mutated human tumor suppressor genes, implicated in cell growth and survival and …

[HTML][HTML] Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer …

…, E Kalogera, F Zagouri, I Flessas, E Goussetis, A Nonni… - BMC cancer, 2009 - Springer
Background Recent evidence suggests that neutrophil gelatinase-associated lipocalin (NGAL)
expression is induced in many types of human cancer, while detection of its complex with …

The prognostic significance of Hsp70/Hsp90 expression in breast cancer: a systematic review and meta-analysis

…, G Kouraklis, T Psaltopoulou, A Nonni - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Studies have focused on heat shock protein (Hsp) inhibitors as potential
treatment agents in breast cancer, with controversial results. Adopting a pathophysiological …

Soluble human leukocyte antigen-G expression in patients with ductal and lobular breast malignancy

…, E Kalogera, A Sagkriotis, F Zagouri, A Nonni… - Anticancer …, 2012 - ar.iiarjournals.org
Background: Human leukocyte antigen-G (HLA-G) has been closely associated with diagnosis
and prognosis in many types of human cancer. The current study aims to investigate …

Targeting histone deacetylases in malignant melanoma: a future therapeutic agent or just great expectations?

…, N Andreatos, EA Antoniou, A Nonni… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Malignant melanoma is the most aggressive type of skin cancer, with
increasing frequency and mortality. Melanoma is characterized by rapid proliferation and …

Histone deacetylase inhibitors as a novel targeted therapy against non-small cell lung cancer: where are we now and what should we expect?

…, S Kokkineli, EA Antoniou, A Nonni… - Anticancer …, 2018 - ar.iiarjournals.org
Non-small cell lung cancer constitutes the most common type of lung cancer, accounting for
85-90% of lung cancer, and is a leading cause of cancer-related death. Despite the progress …

Claudin-3 and claudin-4: distinct prognostic significance in triple-negative and luminal breast cancer

…, D Keramopoulos, A Kolokythas, A Nonni… - Applied …, 2014 - journals.lww.com
Materials and Methods: A total of 128 cases of breast carcinoma were included in the study.
For all these cases, immunohistochemistry for estrogen and progesterone receptors, Ki-67, …