Cytogenetics of extramedullary manifestations in multiple myeloma

…, AM May, M Engelhardt… - British journal of …, 2013 - Wiley Online Library
Extramedullary disease in patients with multiple myeloma is a rare event, occurring mostly
in advanced disease or relapse. Outcome is poor and prognostic factors predicting the …

Successful treatment of extensive calcifications and acute pulmonary involvement in dermatomyositis with the Janus-Kinase inhibitor tofacitinib–A report of two cases

…, N Venhoff, BC Frye, AM May, P Agarwal, M Rizzi… - Journal of …, 2019 - Elsevier
Introduction Dermatomyositis (DM) can be complicated by calcinosis and interstitial lung
disease (ILD). Calcinosis can be severely debilitating or life-threatening and to date there is no …

T and B lymphocyte abnormalities in bone marrow biopsies of common variable immunodeficiency

…, S Goldacker, AM May, M Rizzi… - Blood, The Journal …, 2011 - ashpublications.org
In common variable immunodeficiency (CVID) defects in early stages of B-cell development,
bone marrow (BM) plasma cells and T lymphocytes have not been studied systematically. …

Valproate and retinoic acid in combination with decitabine in elderly nonfit patients with acute myeloid leukemia: results of a multicenter, randomized, 2× 2, phase II …

…, M De Wit, R Wäsch, H Becker, AM May… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE DNA-hypomethylating agents are studied in combination with other epigenetic
drugs, such as histone deacetylase inhibitors or differentiation inducers (eg, retinoids), in …

[HTML][HTML] DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase …

…, B Lubrich, AM May, C Cieslik, MJ Müller, M Lübbert - BMC cancer, 2015 - Springer
Background Acute myeloid leukemia (AML) is predominantly a disease of older patients
with a poor long-term survival. Approval of decitabine (DAC) in the European Union (EU) in …

[HTML][HTML] Large registry analysis to accurately define second malignancy rates and risks in a well-characterized cohort of 744 consecutive multiple myeloma patients …

…, AM May, M Schumacher, M Kleber… - …, 2015 - ncbi.nlm.nih.gov
Additional malignancies in multiple myeloma patients after first-line and maintenance
treatment have been observed, questioning whether specific risks exist. Second primary …

Biallelic expression of mucin-1 in autosomal dominant tubulointerstitial kidney disease: implications for nongenetic disease recognition

…, F Pfister, M Schueler, D Seven, AM May… - Journal of the …, 2018 - journals.lww.com
Background Providing the correct diagnosis for patients with tubulointerstitial kidney disease
and secondary degenerative disorders, such as hypertension, remains a challenge. The …

[HTML][HTML] Intratibial injection of human multiple myeloma cells in NOD/SCID IL-2Rγ (null) mice mimics human myeloma and serves as a valuable tool for the …

…, AM May, R Wäsch, HH Fiebig, M Engelhardt - PloS one, 2013 - journals.plos.org
Background We systematically analyzed multiple myeloma (MM) cell lines and patient bone
marrow cells for their engraftment capacity in immunodeficient mice and validated the …

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial

…, G Babaryka, M Asslaber, K Bodó, M Den Bakker… - Virchows Archiv, 2014 - Springer
The aim of our study was to evaluate the quality of histo- and cytomorphological features of
PAXgene-fixed specimens and their suitability for histomorphological classification in …

Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia

…, M Trepel, AM May, R Engelhardt, M Lübbert - Annals of …, 2012 - Springer
Spontaneous complete remission (CR) is a rare, poorly understood phenomenon in acute
myeloid leukemia (AML). We describe the 10-year follow-up of a patient with MLL-AF9-…