The hairless mouse in skin research

F Benavides, TM Oberyszyn, AM VanBuskirk… - Journal of …, 2009 - Elsevier
The hairless (Hr) gene encodes a transcriptional co-repressor highly expressed in the
mammalian skin. In the mouse, several null and hypomorphic Hr alleles have been identified …

A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family.

A Vanbuskirk, BL Crump, E Margoliash… - The Journal of …, 1989 - rupress.org
The T cell recognition of globular protein antigens requires the processing and presentation
of the antigen by Ia-expressing APCs. Processing is believed to involve the uptake of …

A phase I study of interleukin 12 with trastuzumab in patients with human epidermal growth factor receptor-2-overexpressing malignancies: analysis of sustained …

…, C De Hoff, JE Dierksheide, AM VanBuskirk… - Clinical Cancer …, 2004 - AACR
Purpose: On the basis of preclinical studies, we hypothesized that interleukin (IL)12 would
potentiate the antitumor actions of an antihuman epidermal growth factor receptor-2 (HER2) …

Are th2 helper t lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival? 1

JR Piccotti, SY Chan, AM VanBuskirk… - …, 1997 - journals.lww.com
It is widely accepted that Th1 helper T lymphocytes (HTL)* initiate allograft rejection by
promoting the development of alloantigen-specific cytotoxic T lymphocytes (CTL) and delayed-…

Peptide vaccines incorporating a 'promiscuous' T‐cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity

…, YH Seo, H Lee, AM Vanbuskirk… - Journal of Molecular …, 1993 - Wiley Online Library
An ideal peptide vaccine should contain both B‐ and T‐cell epitopes. Recognition of
antigen by B cells is highly dependent on the three‐dimensional conformation of the antigen …

[HTML][HTML] Clinical significance of MHC-reactive alloantibodies that develop after kidney or kidney–pancreas transplantation

…, PK Hennessy, PW Adams, AM VanBuskirk… - American journal of …, 2002 - Elsevier
The purpose of this study was to determine the relationships between acute rejection, anti-major
histocompatibility complex (MHC) class I and/or class II-reactive alloantibody production…

[HTML][HTML] Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A

BC Wulff, DF Kusewitt, AM VanBuskirk… - Journal of investigative …, 2008 - Elsevier
Transplant immunosuppressants have been implicated in the increased incidence of non-melanoma
skin cancer in transplant recipients, most of whom harbor considerable UVB-…

TRANSFUSION OF POLARIZED TH2-LIKE CELL POPULATIONS INTO SCID MOUSE CARDIAC ALLOGRAFT RECIPIENTS RESULTS IN ACUTE ALLOGRAFT …

AM VanBuskirk, ME Wakely, CG Orosz - Transplantation, 1996 - journals.lww.com
It has been hypothesized that TH1 cells mediate the archetypical cell-mediated immune
response of acute allograft rejection, whereas TH2 cells promote allograft acceptance. To test …

[HTML][HTML] Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast cancer in mice independently of the PPARγ ligand rosiglitazone

LD Yee, DC Young, TJ Rosol, AM VanBuskirk… - The Journal of …, 2005 - Elsevier
Overexpression of human epidermal growth factor receptor 2 (HER-2/neu) characterizes a
molecular subtype of breast cancer associated with poor clinical outcome. Preventive …

PREVENTION OF MURINE CARDIAC ALLOGRAFT REJECTION WITH GALLIUM NITRATE: Comparison with Anti-CD4 Monoclonal Antibody: 1

…, E Wakely, SD Bergese, AM VanBuskirk… - …, 1996 - journals.lww.com
Gallium nitrate (GN) was evaluated for its ability to interfere with acute rejection of DBA/2→
C457BL/6 heterotopic cardiac allografts, in comparison with the depleting anti-CD4 mAb, GK1…