p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells

…, F Guerra, A Pession, AM Ferreri - Oncology …, 2005 - spandidos-publications.com
Histone acetyltransferase and histone deacetylase (HDAC) determine the acetylation status
of histones, and thereby control the regulation of gene expression. HDAC inhibitors have …

Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells

…, AM Ferreri, P Rocchi, F Guerra, M Orlandi - Anticancer …, 2010 - ar.iiarjournals.org
Valproic acid (VPA) is an established drug in the long-term therapy of epilepsy. Recently,
VPA has demonstrated antitumor activity as a histone deacetylase (HDAC) inhibitor. In this …

RXRγ and PPARγ ligands in combination to inhibit proliferation and invasiveness in colon cancer cells

A Papi, P Rocchi, AM Ferreri, M Orlandi - Cancer letters, 2010 - Elsevier
Nuclear retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs
are potential candidates as drug target for cancer prevention and treatment. We …

Toxic, DNA-damaging and mutagenic activity of epichlorohydrin on human cells cultured in vitro

P Perocco, P Rocchi, AM Ferreri… - Tumori Journal, 1983 - journals.sagepub.com
Epichlorohydrin (ECHH) highly inhibited the tritiated thymidine uptake by human lymphocytes
cultured in vitro, although the corresponding cell viability was unaffected. Furthermore, it …

Cytoplasmic receptors for 17β-estradiol, 5α-dihydrotestosterone and progesterone in normal and abnormal human uterine tissues

S Grilli, AM Ferreri, G Gola, R Rocchetta, C Orlandi… - Cancer Letters, 1977 - Elsevier
Determinations of specific cytoplasmic receptors for 17β-estradiol (E), 5α-dihydrotestosterone
(DHT) and progesterone (P) in normal and abnormal endometrium are reported. The …

Simple and Dendritic Cyclam Derivatives. Photophysical Properties, Effect of Protonation and Zn2+ Coordination, Preliminary Screening as Inhibitors of Tumour Cell …

…, S Tavolari, P Rocchi, AM Ferreri - Supramolecular …, 2004 - Taylor & Francis
<p>We have synthesized two novel dendrimers (<bold>BG1</bold> and <bold>BG2</bold>)
consisting of a 1,4,8,11-tetraazacyclotetradecane (cyclam, <bold>1</bold>) core with …

Polycyclic hydrocarbons induction of diphtheria toxin-resistant mutants in human cells

P Rocchi, AM Ferreri, R Borgia, G Prodi - Carcinogenesis, 1980 - academic.oup.com
Stable spontaneous mutants resistant to diphtheria toxin are present in the human cell line (EUE)
at a frequency of 0–8×10 −6 . Mutation increases by a number of polycyclic …

In vivo and in vitro binding of ethionine with nucleic acids

S Grilli, AM FERRERI, P ROCCHI… - GANN Japanese Journal …, 1974 - jstage.jst.go.jp
Treatment of Animals Rats, in groups of 3, were injected intraperitoneally with 14C-ethionine(326μCi
corresponding to 367μmol/kg) or 3H-ethionine(4mCi corrcsponding to 3.07 mmol/…

Secondary infections worsen the outcome of COVID‐19 in patients with hematological malignancies: A report from the ITA‐HEMA‐COV

…, A Maria Scattolin, A Maria Vannucchi… - Hematological …, 2022 - Wiley Online Library
The impact of secondary infections (SI) on COVID‐19 outcome in patients with hematological
malignancies (HM) is scarcely documented. To evaluate incidence, clinical characteristics, …

Induction of diphtheria toxin-resistant mutants in human cells by ultraviolet light

P Rocchi, AM Ferreri, A Capucci, G Prodi - Carcinogenesis, 1981 - academic.oup.com
Stable spontaneous mutants resistant to the protein synthesis inhibitor diphtheria toxin (DT)
have been selected in human cell line EUE at a very low frequency (<8 × 10 −6 ). Uv-…