Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy

A Mukerjee, JK Vishwanatha - Anticancer research, 2009 - ar.iiarjournals.org
Background: Among the potent anticancer agents, curcumin has been found to be very
efficacious against many different types of cancer cells. However, the major disadvantage …

Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis

AP Ranjan, A Mukerjee, L Helson, R Gupta… - Anticancer …, 2013 - ar.iiarjournals.org
Background: Liposome-based drug delivery has been successful in the past decade, with
some formulations being Food and Drug Administration (FDA)-approved and others in clinical …

[HTML][HTML] Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy

AP Ranjan, A Mukerjee, L Helson… - Journal of …, 2012 - Springer
Background Nanoparticle based delivery of anticancer drugs have been widely investigated.
However, a very important process for Research & Development in any pharmaceutical …

Spectroscopic properties of curcumin: orientation of transition moments

A Mukerjee, TJ Sørensen, AP Ranjan… - The Journal of …, 2010 - ACS Publications
Curcumin, a naturally occurring yellow-orange pigment with potent antioxidant and antitumor
properties, has been attracting researchers from a wide range of fields including chemistry, …

[HTML][HTML] Development of biodegradable nanocarriers loaded with a monoclonal antibody

A Gdowski, A Ranjan, A Mukerjee… - International Journal of …, 2015 - mdpi.com
Treatments utilizing monoclonal antibody therapeutics against intracellular protein-protein
interactions in cancer cells have been hampered by several factors, including poor …

Targeted nanocurcumin therapy using annexin A2 antibody improves tumor accumulation and therapeutic efficacy against highly metastatic breast cancer

A Mukerjee, AP Ranjan… - Journal of biomedical …, 2016 - ingentaconnect.com
A major challenge in pharmaceutical research is effective targeting strategies to their sites
of action. Emerging knowledge and the current progress in nanotechnology based delivery …

Curcumin-ER prolonged subcutaneous delivery for the treatment of non-small cell lung cancer

AP Ranjan, A Mukerjee, A Gdowski… - Journal of …, 2016 - ingentaconnect.com
Non-small-cell lung cancer therapy is a challenge due to poor prognosis and low survival
rate. There is an acute need for advanced therapies having higher drug efficacy, low …

Curcumin-loaded Poly (d, l-lactide-co-glycolide) nanovesicles induce antinociceptive effects and reduce pronociceptive cytokine and BDNF release in spinal cord after …

…, AP Ranjan, A Di Giannuario, A Mukerjee… - Colloids and Surfaces B …, 2017 - Elsevier
Given the poor bioavailability of curcumin, its antinociceptive effects are produced after
chronic intravenous administration of high doses, while poly (d,l-lactide-co-glycolide)-loaded …

Fluorescence detection of MMP-9. I. MMP-9 selectively cleaves lys-gly-pro-arg-ser-leu-ser-gly-lys peptide

R Fudala, AP Ranjan, A Mukerjee… - Current …, 2011 - ingentaconnect.com
MMP-9 enzyme recognizes a peptide sequence Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys and
cleaves the peptide into two parts. We synthesized a dual fluorophore beacon consisting of 5-…

Nanobiosensors: role in cancer detection and diagnosis

A Gdowski, AP Ranjan, A Mukerjee… - Infectious Diseases and …, 2014 - Springer
The ability to detect many cancers at an early stage in its clinical course has the potential to
improve patient outcomes in terms of morbidity and mortality. Nanosized components …