Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy
A Mukerjee, JK Vishwanatha - Anticancer research, 2009 - ar.iiarjournals.org
Background: Among the potent anticancer agents, curcumin has been found to be very
efficacious against many different types of cancer cells. However, the major disadvantage …
efficacious against many different types of cancer cells. However, the major disadvantage …
Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis
AP Ranjan, A Mukerjee, L Helson, R Gupta… - Anticancer …, 2013 - ar.iiarjournals.org
Background: Liposome-based drug delivery has been successful in the past decade, with
some formulations being Food and Drug Administration (FDA)-approved and others in clinical …
some formulations being Food and Drug Administration (FDA)-approved and others in clinical …
[HTML][HTML] Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy
AP Ranjan, A Mukerjee, L Helson… - Journal of …, 2012 - Springer
Background Nanoparticle based delivery of anticancer drugs have been widely investigated.
However, a very important process for Research & Development in any pharmaceutical …
However, a very important process for Research & Development in any pharmaceutical …
Spectroscopic properties of curcumin: orientation of transition moments
A Mukerjee, TJ Sørensen, AP Ranjan… - The Journal of …, 2010 - ACS Publications
Curcumin, a naturally occurring yellow-orange pigment with potent antioxidant and antitumor
properties, has been attracting researchers from a wide range of fields including chemistry, …
properties, has been attracting researchers from a wide range of fields including chemistry, …
[HTML][HTML] Development of biodegradable nanocarriers loaded with a monoclonal antibody
Treatments utilizing monoclonal antibody therapeutics against intracellular protein-protein
interactions in cancer cells have been hampered by several factors, including poor …
interactions in cancer cells have been hampered by several factors, including poor …
Targeted nanocurcumin therapy using annexin A2 antibody improves tumor accumulation and therapeutic efficacy against highly metastatic breast cancer
A Mukerjee, AP Ranjan… - Journal of biomedical …, 2016 - ingentaconnect.com
A major challenge in pharmaceutical research is effective targeting strategies to their sites
of action. Emerging knowledge and the current progress in nanotechnology based delivery …
of action. Emerging knowledge and the current progress in nanotechnology based delivery …
Curcumin-ER prolonged subcutaneous delivery for the treatment of non-small cell lung cancer
Non-small-cell lung cancer therapy is a challenge due to poor prognosis and low survival
rate. There is an acute need for advanced therapies having higher drug efficacy, low …
rate. There is an acute need for advanced therapies having higher drug efficacy, low …
Curcumin-loaded Poly (d, l-lactide-co-glycolide) nanovesicles induce antinociceptive effects and reduce pronociceptive cytokine and BDNF release in spinal cord after …
…, AP Ranjan, A Di Giannuario, A Mukerjee… - Colloids and Surfaces B …, 2017 - Elsevier
Given the poor bioavailability of curcumin, its antinociceptive effects are produced after
chronic intravenous administration of high doses, while poly (d,l-lactide-co-glycolide)-loaded …
chronic intravenous administration of high doses, while poly (d,l-lactide-co-glycolide)-loaded …
Fluorescence detection of MMP-9. I. MMP-9 selectively cleaves lys-gly-pro-arg-ser-leu-ser-gly-lys peptide
MMP-9 enzyme recognizes a peptide sequence Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys and
cleaves the peptide into two parts. We synthesized a dual fluorophore beacon consisting of 5-…
cleaves the peptide into two parts. We synthesized a dual fluorophore beacon consisting of 5-…
Nanobiosensors: role in cancer detection and diagnosis
The ability to detect many cancers at an early stage in its clinical course has the potential to
improve patient outcomes in terms of morbidity and mortality. Nanosized components …
improve patient outcomes in terms of morbidity and mortality. Nanosized components …