Mammary tumors similar to those observed in women can be induced in rats by intraperitoneal
administration of N-methyl-N-nitrosourea. Determining tumor volume is a useful and …

Oral gavage is a widely used method for administering substances to animals in
pharmacological and toxicological studies. The authors evaluated whether oral gavage causes …

The administration of chemical carcinogens is one of the most commonly used methods to
induce tumors in several organs in laboratory animals in order to study oncologic diseases of …

Chemically-induced mammary tumors in rats by the carcinogens 1-methyl-1-nitrosourea- (MNU)
and 7,12-dimethylbenz[a]anthracene (DMBA) are the most widely used models for …

Histamine is a biogenic amine, synthetized and released by mast cells, which acts as a
vasodilator in several pathologic processes, namely in allergies and conjunctivitis. Its role on …

Background: The Nobel Prize of Physiology or Medicine (NPPM) has recognized the work
of 222 scientists from different nationalities, from 1901 until 2020. From the total, 186 award …

Prostate cancer is the second most common cancer in men, affecting approximately 1.1
million men worldwide. In this way, the study of prostate cancer biopathology and the study of …

Breast cancer is the most common malignancy in women worldwide. Several studies have
suggested that exercise training may decrease the risk of breast cancer development. This …

Colorectal cancer is one of the most common gastrointestinal malignancies in humans, affecting
approximately 1.8 million people worldwide. This disease has a major social impact and …

Essential oils are natural compounds used by humans for scientific purposes due to their
wide range of properties. Eugenol is mostly present in clove oil, while pulegone is the main …