User profiles for AMMAD AHMAD FAROOQI

Ammad Ahmad Farooqi

Institute of Biomedical and Genetic Engineering (IBGE)
Verified email at rlmclahore.com
Cited by 6518

Overview of the oncogenic signaling pathways in colorectal cancer: Mechanistic insights

AA Farooqi, M De La Roche, MBA Djamgoz… - Seminars in cancer …, 2019 - Elsevier
Colorectal cancer is a multifaceted disease which is therapeutically challenging. Based on
insights gleaned from almost a quarter century of research, it is obvious that deregulation of …

Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds

AA Farooqi, NN Desai, MZ Qureshi… - Biotechnology …, 2018 - Elsevier
A rapidly growing body of experimental evidence has begun to shed light on the wide
ranging molecular mechanisms which modulate intra- and inter-cellular communications. A …

[HTML][HTML] Mir-34: a new weapon against cancer?

G Misso, MT Di Martino, G De Rosa, AA Farooqi… - … therapy-nucleic acids, 2014 - cell.com
The microRNA(miRNA)-34a is a key regulator of tumor suppression. It controls the expression
of a plethora of target proteins involved in cell cycle, differentiation and apoptosis, and …

Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention

…, SF Nabavi, SM Nabavi, A Sureda, AA Farooqi… - Pharmacological …, 2018 - Elsevier
Activator protein 1 (AP-1) is a key transcription factor in the control of several cellular
processes responsible for cell survival proliferation and differentiation. Dysfunctional AP-1 …

[HTML][HTML] Toxic-metal-induced alteration in miRNA expression profile as a proposed mechanism for disease development

…, A Pizent, E Renieri, A Tsatsakis, AA Farooqi… - Cells, 2020 - mdpi.com
Toxic metals are extensively found in the environment, households, and workplaces and
contaminate food and drinking water. The crosstalk between environmental exposure to toxic …

Platelet‐derived growth factor (PDGF) signalling in cancer: rapidly emerging signalling landscape

AA Farooqi, ZH Siddik - Cell biochemistry and function, 2015 - Wiley Online Library
Platelet‐derived growth factor (PDGF)‐mediated signalling has emerged as one of the most
extensively and deeply studied biological mechanism reported to be involved in regulation …

[HTML][HTML] PI3K/AKT/mTOR pathway in ovarian cancer treatment: are we on the right track?

…, I Ruscito, A Papadia, AA Farooqi… - Geburtshilfe und …, 2017 - thieme-connect.com
The high recurrence rate and the low overall survival in ovarian cancer suggest that a more
specific therapeutic approach in addition to conventional treatment is required. Translational …

ATM protein kinase: the linchpin of cellular defenses to stress

S Bhatti, S Kozlov, AA Farooqi, A Naqi, M Lavin… - Cellular and Molecular …, 2011 - Springer
ATM is the most significant molecule involved in monitoring the genomic integrity of the cell.
Any damage done to DNA relentlessly challenges the cellular machinery involved in …

[HTML][HTML] Oleanolic acid alters multiple cell signaling pathways: implication in cancer prevention and therapy

…, A Mocan, SF Nabavi, A Bishayee, AA Farooqi… - International journal of …, 2017 - mdpi.com
Nowadays, much attention has been paid to diet and dietary supplements as a cost-effective
therapeutic strategy for prevention and treatment of a myriad of chronic and degenerative …

[HTML][HTML] Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress

AA Farooqi, KT Li, S Fayyaz, YT Chang, M Ismail… - Tumor Biology, 2015 - Springer
Prior research has demonstrated how the endoplasmic reticulum (ER) functions as a
multifunctional organelle and as a well-orchestrated protein-folding unit. It consists of sensors …