[HTML][HTML] Tamoxifen and endometrial cancer: a Janus-headed drug

G Emons, A Mustea, C Tempfer - Cancers, 2020 - mdpi.com
Simple Summary Tamoxifen, an antiestrogen, is a potent drug to treat and prevent hormone
dependent breast cancer. As it has low toxicity and is widely available, tamoxifen has …

[HTML][HTML] A randomized trial of lymphadenectomy in patients with advanced ovarian neoplasms

…, G Aletti, W Meier, D Cibula, A Mustea… - … England Journal of …, 2019 - Mass Medical Soc
Background Systematic pelvic and paraaortic lymphadenectomy has been widely used in the
surgical treatment of patients with advanced ovarian cancer, although supporting evidence …

Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM

…, C Rupp, A Stoeck, Y Issa, D Koensgen, A Mustea… - Gynecologic …, 2007 - Elsevier
OBJECTIVE.: CD24 is an established marker for poor prognosis in ovarian and other
carcinomas. Acquisition of cytoplasmic CD24, as opposed to membranous expression, has been …

Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

…, HD Volk, U Hoffmüller, A Grützkau, A Mustea… - Cancer research, 2009 - AACR
Regulatory T-cells (Treg) have been the focus of immunologic research due to their role in
establishing tolerance for harmless antigens versus allowing immune responses against foes. …

Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes

…, F Marmé, S Runz, S Wolterink, D Koensgen, A Mustea… - Cancer letters, 2009 - Elsevier
Exosomes are membrane vesicles that are released from many different cell types. Tumor
derived-exosomes play a role in immune suppression. We hypothesized that in ovarian …

The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications

…, C Fotopoulou, P Harter, C Kurzeder, A Mustea… - Archives of gynecology …, 2016 - Springer
Introduction Molecular pathological research has contributed to improving the knowledge of
different subtypes of ovarian cancer. In parallel with the implementation of the new FIGO …

Serum C-reactive protein as independent prognostic variable in patients with ovarian cancer

…, N Concin, G Hofstetter, C Marth, A Mustea… - Clinical cancer …, 2008 - AACR
Purpose: To evaluate serum C-reactive protein (CRP) as prognostic variable in patients with
epithelial ovarian cancer (EOC). Experimental Design: In a multicenter study, preoperative …

Adjuvant therapy in lymph node–positive vulvar cancer: the AGO-CaRE-1 study

…, K Baumann, F Thiel, A Mustea… - Journal of the …, 2015 - academic.oup.com
Background: Women with node-positive vulvar cancer have a high risk for disease recurrence.
Indication criteria for adjuvant radiotherapy are controversial. This study was designed to …

Granulosa cell tumor of the ovary: 10 years follow-up data of 65 patients

J Sehouli, FS Drescher, A Mustea, D Elling… - Anticancer …, 2004 - ar.iiarjournals.org
Background: Granulosa cell tumor of the ovary is an uncommon neoplasm. The majority of
patients are diagnosed in early stages of disease and overall prognosis is favorable. The …

Membranous NECTIN-4 expression frequently decreases during metastatic spread of urothelial carcinoma and is associated with enfortumab vedotin resistance

…, M Abbas, S Zschäbitz, C Schwab, A Mustea… - Clinical Cancer …, 2023 - AACR
Purpose: The antibody–drug conjugate enfortumab vedotin (EV) releases a cytotoxic agent
into tumor cells via binding to the membrane receptor NECTIN-4. EV was recently approved …