Selective follicular targeting by modification of the particle sizes

A Patzelt, H Richter, F Knorr, U Schäfer, CM Lehr… - Journal of controlled …, 2011 - Elsevier
Hair follicles represent interesting target sites for topically applied substances such as topical
vaccinations or agents used in the field of regenerative medicine. In recent years, it could …

Follicular transport route–research progress and future perspectives

F Knorr, J Lademann, A Patzelt, W Sterry… - European Journal of …, 2009 - Elsevier
The important role of hair follicles as penetration pathways and reservoir structures for
topically applied compounds has been validated in numerous animal models as well as in …

The role of hair follicles in the percutaneous absorption of caffeine

N Otberg, A Patzelt, U Rasulev… - British journal of …, 2008 - Wiley Online Library
… Dr Alexa Patzelt MD, Center of Experimental and Applied Physiology, Department of
Dermatology, Charité-Universitaetsmedizin-Berlin, Charitéplatz 1, 10117 Berlin, Germany. Tel.: + …

Drug delivery to hair follicles

A Patzelt, J Lademann - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: The optimization of drug delivery to and via the hair follicles is gaining more and
more importance as it has been recognized that the hair follicles are an interesting target …

One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors

ME Darvin, A Patzelt, F Knorr… - … of biomedical optics, 2008 - spiedigitallibrary.org
Variation in the level of the carotenoid antioxidant substances beta-carotene and lycopene
in the human skin of ten healthy volunteers was measured with resonance Raman …

Cutaneous concentration of lycopene correlates significantly with the roughness of the skin

M Darvin, A Patzelt, S Gehse, S Schanzer… - European Journal of …, 2008 - Elsevier
Antioxidant substances in the skin are expected to slow down photo ageing. We therefore
developed the hypothesis that high levels of antioxidant substances may be correlated to …

Risk assessment of the application of a plasma jet in dermatology

…, A Alborova, D Humme, A Patzelt… - … of biomedical optics, 2009 - spiedigitallibrary.org
Regardless of the fact that several highly efficient antiseptics are commercially available,
the antiseptic treatment of chronic wounds remains a problem. In the past, electrical plasma …

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

…, N Otberg, S Trauer, A Patzelt… - British journal of …, 2011 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Depending on the body site and the
substances, the hair follicles can contribute significantly to the penetration of topically …

Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data

S Trauer, A Patzelt, N Otberg, F Knorr… - British journal of …, 2009 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The hair follicles represent important
shunt routes into the skin for a multiplicity of drugs and chemicals. Recently, it has been …

Determination of the cuticula thickness of human and porcine hairs and their potential influence on the penetration of nanoparticles into the hair follicles

J Lademann, A Patzelt, H Richter… - … of biomedical optics, 2009 - spiedigitallibrary.org
An efficient penetration and long-term storage of topically applied substances is important for
drug delivery in medical treatment and cosmetics. It has recently become apparent that the …