Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and …
S Lev-Ari, A Starr, A Vexler, V Karaush… - Anticancer …, 2006 - ar.iiarjournals.org
Background: Several studies suggested that curcumin inhibits growth of malignant cells via
inhibition of cyclooxygenase-2 (COX-2) activity. Other studies indicated that epidermal …
inhibition of cyclooxygenase-2 (COX-2) activity. Other studies indicated that epidermal …
Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA
E Sagiv, A Starr, U Rozovski, R Khosravi, P Altevogt… - Cancer research, 2008 - AACR
CD24 is a potential oncogene reported to be overexpressed in a large variety of human
malignancies. We have shown that CD24 is overexpressed in 90% of colorectal tumors at a fairly …
malignancies. We have shown that CD24 is overexpressed in 90% of colorectal tumors at a fairly …
Curcumin augments gemcitabine cytotoxic effect on pancreatic adenocarcinoma cell lines
S Lev-Ari, A Vexler, A Starr… - Cancer …, 2007 - Taylor & Francis
Background and aim: Gemcitabine, the first-line agent in pancreatic adenocarcinoma, has
shown limited clinical benefit. Cyclooxygenase-2 (COX-2) represent one of the most …
shown limited clinical benefit. Cyclooxygenase-2 (COX-2) represent one of the most …
Curcumin: A potential radio‐enhancer in head and neck cancer
Objectives/Hypothesis: To investigate whether curcumin enhances the cytotoxic effect of
radiotherapy in head and neck squamous cell carcinoma (HNSCC). Methods: HNSCC cell lines …
radiotherapy in head and neck squamous cell carcinoma (HNSCC). Methods: HNSCC cell lines …
[PDF][PDF] Post-transcriptional inhibition of Hsc70-4/HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of ALS
Amyotrophic lateral sclerosis (ALS) is a synaptopathy accompanied by the presence of
cytoplasmic aggregates containing TDP-43, an RNA-binding protein linked to ∼97% of ALS …
cytoplasmic aggregates containing TDP-43, an RNA-binding protein linked to ∼97% of ALS …
Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS
…, D Barrameda, AG O'Conner, JM Barrows, A Starr… - Elife, 2019 - elifesciences.org
10.7554/eLife.45114.001 Amyotrophic Lateral Sclerosis (ALS), is a fatal neurodegenerative
disorder, with TDP-43 inclusions as a major pathological hallmark. Using a Drosophila …
disorder, with TDP-43 inclusions as a major pathological hallmark. Using a Drosophila …
ErbB4 increases the proliferation potential of human lung cancer cells and its blockage can be used as a target for anti‐cancer therapy
A Starr, J Greif, A Vexler… - … journal of cancer, 2006 - Wiley Online Library
Clinical and experimental data suggest that ErbB‐4, a member of the epidermal growth
factor receptor family, may have a role in cancer progression and response to treatment. We …
factor receptor family, may have a role in cancer progression and response to treatment. We …
Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD
A Starr, R Sattler - Brain research, 2018 - Elsevier
Amyotrophic lateral sclerosis (ALS) is characterized by a progressive degeneration of upper
and lower motor neurons, resulting in fatal paralysis due to denervation of the muscle. Due …
and lower motor neurons, resulting in fatal paralysis due to denervation of the muscle. Due …
An immunoconjugate of anti-CD24 and Pseudomonas exotoxin selectively kills human colorectal tumors in mice
S Shapira, A Shapira, A Starr, D Kazanov, S Kraus… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Effective and selective treatment options are needed for patients
with colorectal cancer (CRC). The CD24 mucin-like glycoprotein is overexpressed in CRCs; …
with colorectal cancer (CRC). The CD24 mucin-like glycoprotein is overexpressed in CRCs; …
Curcumin induces apoptosis and inhibits growth of orthotopic human non-small cell lung cancer xenografts
S Lev-Ari, A Starr, S Katzburg, L Berkovich… - The Journal of nutritional …, 2014 - Elsevier
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality. Curcumin
is involved in various biological pathways leading to inhibition of NSCLC growth. The …
is involved in various biological pathways leading to inhibition of NSCLC growth. The …