Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk
Deletions on human chromosome 8p22–23 in prostate cancer cells 1 and linkage studies in
families affected with hereditary prostate cancer (HPC) 2, 3, 4 have implicated this region in …
families affected with hereditary prostate cancer (HPC) 2, 3, 4 have implicated this region in …
A Germline DNA Polymorphism Enhances Alternative Splicing of the KLF6 Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk
…, E Hod, A Katz, WB Isaacs, S Hebbring, A Komiya… - Cancer research, 2005 - AACR
Prostate cancer is a leading and increasingly prevalent cause of cancer death in men. Whereas
family history of disease is one of the strongest prostate cancer risk factors and suggests …
family history of disease is one of the strongest prostate cancer risk factors and suggests …
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter its DNA-binding specificity
…, EW Moerland, CJ Cornelisse, H Suzuki, A Komiya… - Cancer research, 2002 - AACR
CTCF is a widely expressed 11-zinc finger (ZF) transcription factor that is involved in
different aspects of gene regulation including promoter activation or repression, hormone-…
different aspects of gene regulation including promoter activation or repression, hormone-…
Codon 877 mutation in the androgen receptor gene in advanced prostate cancer: relation to antiandrogen withdrawal syndrome
H Suzuki, K Akakura, A Komiya, S Aida… - The …, 1996 - Wiley Online Library
The growth of prostate cancer is androgen responsive, and androgen receptor (AR) is
thought to play an important role in the development of this cancer. Recently, some reports …
thought to play an important role in the development of this cancer. Recently, some reports …
Neuroendocrine differentiation in the progression of prostate cancer
A Komiya, H Suzuki, T Imamoto… - … Journal of Urology, 2009 - Wiley Online Library
Neuroendocrine (NE) cells originally exist in the normal prostate acini and duct, regulating
prostatic growth, differentiation and secretion. Clusters of malignant NE cells are found in …
prostatic growth, differentiation and secretion. Clusters of malignant NE cells are found in …
Pretreatment serum testosterone level as a predictive factor of pathological stage in localized prostate cancer patients treated with radical prostatectomy
…, S Fukasawa, M Shimbo, M Inahara, A Komiya… - European urology, 2005 - Elsevier
OBJECTIVE:: Pretreatment serum level of testosterone (T) is a potential prognostic factor for
prostate cancer. The present study was conducted to evaluate the clinical significance of …
prostate cancer. The present study was conducted to evaluate the clinical significance of …
Chromogranin a concentration as a serum marker to predict prognosis after endocrine therapy for prostate cancer
S Isshiki, K Akakura, A Komiya, H Suzuki… - The Journal of …, 2002 - auajournals.org
Purpose : Chromogranin A is gaining acceptance as a serum marker of neuroendocrine
tumors and the concentration is thought to be elevated in relation to neuroendocrine …
tumors and the concentration is thought to be elevated in relation to neuroendocrine …
Pretreatment serum level of neuron specific enolase (NSE) as a prognostic factor in metastatic prostate cancer patients treated with endocrine therapy
N Kamiya, K Akakura, H Suzuki, S Isshiki, A Komiya… - European urology, 2003 - Elsevier
Objective: The serum level of neuron specific enolase (NSE) is gaining acceptance as a
marker of neuroendocrine tumors. To clarify the role of NSE in prostate cancer progression, we …
marker of neuroendocrine tumors. To clarify the role of NSE in prostate cancer progression, we …
The role of testosterone in the pathogenesis of prostate cancer
…, N Kamiya, K Araki, A Komiya… - … journal of urology, 2008 - Wiley Online Library
Relationships between androgenic hormones and prostatic tissue growth are complex. It is
certainly true that the prostate will not develop without androgens and the gland will atrophy if …
certainly true that the prostate will not develop without androgens and the gland will atrophy if …
High predictive accuracy of Aldosteronoma Resolution Score in Japanese patients with aldosterone-producing adenoma
…, K Kawamura, T Imamoto, N Kamiya, A Komiya… - Surgery, 2012 - Elsevier
BACKGROUND: Primary aldosteronism caused by aldosterone-producing adenoma is the
most common curable cause of secondary hypertension, but despite resection, many patients …
most common curable cause of secondary hypertension, but despite resection, many patients …